CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-011215
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 ER-derived vesicles protein ERV41 
Protein Synonyms/Alias
  
Gene Name
 ERV41 
Gene Synonyms/Alias
 YML067C 
Created Date
 July 27, 2013 
Organism
 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) 
NCBI Taxa ID
 559292 
Lysine Modification
Position
Peptide
Type
References
12KTFDAFPKTEEQYKKubiquitination[1]
191LGYVASRKAPLEELKubiquitination[1]
247VVPTLFKKLGAEVDTubiquitination[1]
347YQPDDKTKGILDR**ubiquitination[1]
Reference
 [1] Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation.
 Swaney DL, Beltrao P, Starita L, Guo A, Rush J, Fields S, Krogan NJ, VillĂ©n J.
 Nat Methods. 2013 Jul;10(7):676-82. [PMID: 23749301
Functional Description
 Constituent of COPII-coated endoplasmic reticulum- derived transport vesicles. Required for efficient transport of a subset of secretory proteins to the Golgi. The C-terminal Ile-Leu motif is required for exit from the endoplasmic reticulum. Facilitates retrograde transport from the Golgi to the endoplasmic reticulum. 
Sequence Annotation
 MOTIF 349 350 Isoleucine-leucine motif.  
Keyword
 3D-structure; Complete proteome; Direct protein sequencing; Endoplasmic reticulum; ER-Golgi transport; Golgi apparatus; Membrane; Protein transport; Reference proteome; Transmembrane; Transmembrane helix; Transport. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 352 AA 
Protein Sequence
MAGLKTFDAF PKTEEQYKKK STKGGLTSLL TYLFLLFIAW TEFGEYFGGY IDQQYVVDSQ 60
VRDTVQINMD IYVNTKCDWL QINVRDQTMD RKLVLEELQL EEMPFFIPYD TKVNDINEII 120
TPELDEILGE AIPAEFREKL DTRSFFDESD PNKAHLPEFN GCHVFGSIPV NRVSGELQIT 180
AKSLGYVASR KAPLEELKFN HVINEFSFGD FYPYIDNPLD NTAQFNQDEP LTTYVYYTSV 240
VPTLFKKLGA EVDTNQYSVN DYRYLYKDVA AKGDKMPGIF FKYNFEPLSI VVSDVRLSFI 300
QFLVRLVAIC SFLVYCASWI FTLLDMALIT IMGPKWSLRY QPDDKTKGIL DR 352 
Gene Ontology
 GO:0033116; C:endoplasmic reticulum-Golgi intermediate compartment membrane; IEA:UniProtKB-SubCell.
 GO:0030134; C:ER to Golgi transport vesicle; IDA:SGD.
 GO:0030176; C:integral to endoplasmic reticulum membrane; IDA:SGD.
 GO:0030173; C:integral to Golgi membrane; IDA:SGD.
 GO:0006888; P:ER to Golgi vesicle-mediated transport; IPI:SGD.
 GO:0015031; P:protein transport; IEA:UniProtKB-KW. 
Interpro
 IPR027198; Erv41/Erv46.
 IPR012936; Erv_C. 
Pfam
 PF07970; COPIIcoated_ERV 
SMART
  
PROSITE
  
PRINTS