UniProt Accession

 HP1B3_MOUSE; Q3TEA8; A2AM64; A2AM68; Q3TM38; Q3TU07; Q61688; Q8BT17; Q8C6H2; Q8C911; Q8VE06; Q99KR0; Q9DBI1 

Genbank Protein ID

 AK004938; AK028181; AK043260; AK075725; AK161041; AK166161; AK169740; AL807249; AL807249; BC004053; BC020024; X99642 

Genbank Nucleotide ID

 BAB23683.1; BAC25794.1; BAC31507.1; BAC35912.1; BAE36164.1; BAE38604.1; BAE41340.1; CAM18860.1; CAM18863.1; AAH04053.1; AAH20024.1; CAA67961.1 

Protein Name

 Heterochromatin protein 1-binding protein 3 

Protein Synonyms/Alias

  

Gene Name

 Hp1bp3 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Mus musculus (Mouse) 

NCBI Taxa ID

 10090 

Lysine Modification

Position	Peptide	Type	References
320	QLEQITGKGASGTFQ	ubiquitination	[1]
469	TPAKSQGKTASMKQR	acetylation	[2]

Reference

 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023]
 [2] SIRT5-Mediated Lysine Desuccinylation Impacts Diverse Metabolic Pathways.
 Park J, Chen Y, Tishkoff DX, Peng C, Tan M, Dai L, Xie Z, Zhang Y, Zwaans BM, Skinner ME, Lombard DB, Zhao Y.
 Mol Cell. 2013 Jun 27;50(6):919-30. [PMID: 23806337] 

Functional Description

 Component of heterochromatin, may be involved in chromatin structure and function. 

Sequence Annotation

 DOMAIN 159 234 H15 1.
 DOMAIN 255 330 H15 2.
 DOMAIN 337 413 H15 3.
 MOD_RES 2 2 N-acetylalanine (By similarity).
 MOD_RES 6 6 Phosphoserine (By similarity).
 MOD_RES 51 51 Phosphothreonine.
 MOD_RES 144 144 Phosphoserine (By similarity).
 MOD_RES 157 157 Phosphoserine (By similarity).
 MOD_RES 158 158 Phosphoserine (By similarity).
 MOD_RES 249 249 Phosphoserine (By similarity).
 MOD_RES 431 431 Phosphoserine.
 MOD_RES 443 443 Phosphoserine.
 MOD_RES 444 444 Phosphoserine.
 MOD_RES 447 447 Phosphoserine.  

Keyword

 Acetylation; Alternative splicing; Chromosome; Complete proteome; DNA-binding; Nucleus; Phosphoprotein; Reference proteome; Repeat. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 554 AA 

Protein Sequence

Gene Ontology

 GO:0000786; C:nucleosome; IEA:InterPro.
 GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
 GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
 GO:0006334; P:nucleosome assembly; IEA:InterPro. 

Interpro

 IPR005818; Histone_H1/H5.
 IPR005819; Histone_H5.
 IPR011991; WHTH_DNA-bd_dom. 

Pfam

 PF00538; Linker_histone 

SMART

 SM00526; H15 

PROSITE

 PS51504; H15 

PRINTS

 PR00624; HISTONEH5.