UniProt Accession

 ZWINT_MOUSE; Q9CQU5; Q3UYT8; Q91VI4; Q9D0W9 

Genbank Protein ID

 AK004305; AK008144; AK013556; AK075977; AK134380; BC013559; BC027100; BC034870 

Genbank Nucleotide ID

 BAB23256.1; BAB25492.1; BAB28904.1; BAC36090.1; BAE22123.1; AAH13559.1; AAH27100.1; AAH34870.1 

Protein Name

 ZW10 interactor 

Protein Synonyms/Alias

 ZW10-interacting protein 1; Zwint-1 

Gene Name

 Zwint 

Gene Synonyms/Alias

 D10Ertd749e 

Created Date

 July 27, 2013 

Organism

 Mus musculus (Mouse) 

NCBI Taxa ID

 10090 

Lysine Modification

Position	Peptide	Type	References
160	EKLQLAQKQWVLQQK	ubiquitination	[1]

Reference

 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 

Functional Description

 Part of the MIS12 complex, which is required for kinetochore formation and spindle checkpoint activity. Required to target ZW10 to the kinetochore at prometaphase (By similarity). 

Sequence Annotation

 REGION 86 161 Interaction with NDC80 and ZW10 (By  

Keyword

 Cell cycle; Cell division; Centromere; Chromosome; Coiled coil; Complete proteome; Kinetochore; Mitosis; Nucleus; Reference proteome. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 252 AA 

Protein Sequence

Gene Ontology

 GO:0000777; C:condensed chromosome kinetochore; IEA:UniProtKB-SubCell.
 GO:0005737; C:cytoplasm; IEA:Compara.
 GO:0030425; C:dendrite; IEA:Compara.
 GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
 GO:0051301; P:cell division; IEA:UniProtKB-KW.
 GO:0051649; P:establishment of localization in cell; IEA:Compara.
 GO:0007093; P:mitotic cell cycle checkpoint; IEA:Compara.
 GO:0000070; P:mitotic sister chromatid segregation; IEA:Compara. 

Interpro

  

Pfam

  

SMART

  

PROSITE

  

PRINTS