CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-001894
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Alpha-elapitoxin-Ls2a 
Protein Synonyms/Alias
 Alpha-EPTX-Ls2a; Long neurotoxin Ls3; LsIII; Neurotoxin 1; Neurotoxin alpha 
Gene Name
  
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Pseudolaticauda semifasciata (Black-banded sea krait) (Laticaud 
NCBI Taxa ID
 8631 
Lysine Modification
Position
Peptide
Type
References
44GQEICYVKSWCNAWCacetylation[1]
56AWCSSRGKVLEFGCAacetylation[1]
Reference
 [1] The acetylation of the amino groups of Laticauda semifasciata III, a sea snake venom component.
 Kim HS, Abe T, Tamiya N.
 J Biochem. 1980 Sep;88(3):889-93. [PMID: 7419526
Functional Description
 Binds with high affinity to muscular and neuronal alpha- 7 nicotinic acetylcholine receptors (nAChRs). 
Sequence Annotation
 DISULFID 24 41
 DISULFID 34 62
 DISULFID 47 51
 DISULFID 66 77
 DISULFID 78 83  
Keyword
 3D-structure; Acetylcholine receptor inhibiting toxin; Direct protein sequencing; Disulfide bond; Ion channel impairing toxin; Neurotoxin; Postsynaptic neurotoxin; Secreted; Signal; Toxin. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 87 AA 
Protein Sequence
MKTLLLTLVV VTIVCLDLGY TRECYLNPHD TQTCPSGQEI CYVKSWCNAW CSSRGKVLEF 60
GCAATCPSVN TGTEIKCCSA DKCNTYP 87 
Gene Ontology
 GO:0035792; C:other organism postsynaptic membrane; IEA:UniProtKB-KW.
 GO:0035821; P:modification of morphology or physiology of other organism; IEA:InterPro. 
Interpro
 IPR003571; Snake_toxin.
 IPR018354; Snake_toxin_BS. 
Pfam
 PF00087; Toxin_1 
SMART
  
PROSITE
 PS00272; SNAKE_TOXIN 
PRINTS