UniProt Accession

 STMN3_MOUSE; O70166 

Genbank Protein ID

 AB007912; AF069708; BC057017 

Genbank Nucleotide ID

 BAA28629.1; AAC21575.1; AAH57017.1 

Protein Name

 Stathmin-3 

Protein Synonyms/Alias

 Hippocampus abundant transcript 3; SCG10-like protein; SCG10-related protein HiAT3 

Gene Name

 Stmn3 

Gene Synonyms/Alias

 Sclip 

Created Date

 July 27, 2013 

Organism

 Mus musculus (Mouse) 

NCBI Taxa ID

 10090 

Lysine Modification

Position	Peptide	Type	References
9	ASTVSAYKEKMKELS	ubiquitination	[1]
11	TVSAYKEKMKELSVL	ubiquitination	[1]
78	LSSPPKRKDASLEEL	ubiquitination	[1]
87	ASLEELQKRLEAAEE	ubiquitination	[1]
105	TQEAQVLKQLAERRE	ubiquitination	[1]
135	FSRLAEEKLNYKMEL	ubiquitination	[1]

Reference

 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 

Functional Description

 Exhibits microtubule-destabilizing activity, which is antagonized by STAT3. 

Sequence Annotation

 DOMAIN 38 180 SLD.
 MOD_RES 65 65 Phosphoserine.
 MOD_RES 68 68 Phosphoserine.
 MOD_RES 73 73 Phosphoserine.
 LIPID 22 22 S-palmitoyl cysteine (By similarity).
 LIPID 24 24 S-palmitoyl cysteine (By similarity).  

Keyword

 Cell projection; Coiled coil; Complete proteome; Golgi apparatus; Lipoprotein; Palmitate; Phosphoprotein; Reference proteome. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 180 AA 

Protein Sequence

Gene Ontology

 GO:0030424; C:axon; IEA:UniProtKB-SubCell.
 GO:0005737; C:cytoplasm; IDA:HGNC.
 GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.
 GO:0030426; C:growth cone; IEA:UniProtKB-SubCell.
 GO:0031122; P:cytoplasmic microtubule organization; IDA:HGNC.
 GO:0035021; P:negative regulation of Rac protein signal transduction; IDA:HGNC.
 GO:0031175; P:neuron projection development; IDA:HGNC.
 GO:0051493; P:regulation of cytoskeleton organization; IDA:HGNC.
 GO:0031110; P:regulation of microtubule polymerization or depolymerization; IEA:InterPro.
 GO:0032314; P:regulation of Rac GTPase activity; IDA:HGNC. 

Interpro

 IPR000956; Stathmin_fam. 

Pfam

 PF00836; Stathmin 

SMART

  

PROSITE

 PS00563; STATHMIN_1
 PS01041; STATHMIN_2
 PS51663; STATHMIN_3 

PRINTS

 PR00345; STATHMIN.