CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-008706
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 CCAAT/enhancer-binding protein gamma 
Protein Synonyms/Alias
 C/EBP gamma; Granulocyte colony-stimulating factor promoter element 1-binding protein; GPE1-BP; GPE1-binding protein; Immunoglobulin enhancer-binding protein 1; IG/EBP-1 
Gene Name
 Cebpg 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
113AKIKLLTKELSVLKDubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023
Functional Description
 Transcription factor that binds to the promoter and the enhancer of the immunoglobulin heavy chain. Binds to GPE1, a cis- acting element in the G-CSF gene promoter. 
Sequence Annotation
 DOMAIN 62 125 bZIP.
 REGION 66 93 Basic motif (By similarity).
 REGION 97 118 Leucine-zipper (By similarity).  
Keyword
 Activator; Complete proteome; DNA-binding; Nucleus; Reference proteome; Transcription; Transcription regulation. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 150 AA 
Protein Sequence
MSKLSQPATT PGVNGISVIH TQAHASGLQQ VPQLVPAGPG GGGKAVPPSK QSKKSSPMDR 60
NSDEYRQRRE RNNMAVKKSR LKSKQKAQDT LQRVNQLKEE NERLEAKIKL LTKELSVLKD 120
LFLEHAHSLA DNVQPISTET TATNSDNPGQ 150 
Gene Ontology
 GO:0005634; C:nucleus; IDA:UniProtKB.
 GO:0003690; F:double-stranded DNA binding; IEA:Compara.
 GO:0046982; F:protein heterodimerization activity; ISS:UniProtKB.
 GO:0042803; F:protein homodimerization activity; NAS:UniProtKB.
 GO:0043565; F:sequence-specific DNA binding; ISS:UniProtKB.
 GO:0008134; F:transcription factor binding; ISS:UniProtKB.
 GO:0030183; P:B cell differentiation; IEP:UniProtKB.
 GO:0006338; P:chromatin remodeling; TAS:UniProtKB.
 GO:0043353; P:enucleate erythrocyte differentiation; IMP:UniProtKB.
 GO:0001889; P:liver development; ISS:UniProtKB.
 GO:0016071; P:mRNA metabolic process; IMP:MGI.
 GO:0042267; P:natural killer cell mediated cytotoxicity; IMP:UniProtKB.
 GO:0043433; P:negative regulation of sequence-specific DNA binding transcription factor activity; IDA:UniProtKB.
 GO:0006337; P:nucleosome disassembly; TAS:UniProtKB.
 GO:0045739; P:positive regulation of DNA repair; ISS:UniProtKB.
 GO:0045078; P:positive regulation of interferon-gamma biosynthetic process; IMP:UniProtKB.
 GO:0006357; P:regulation of transcription from RNA polymerase II promoter; ISO:MGI.
 GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. 
Interpro
 IPR004827; bZIP. 
Pfam
 PF07716; bZIP_2 
SMART
 SM00338; BRLZ 
PROSITE
 PS50217; BZIP
 PS00036; BZIP_BASIC 
PRINTS