CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-006905
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Mannosyl phosphorylinositol ceramide synthase CSH1 
Protein Synonyms/Alias
 CSG1/SUR1 homolog 1 
Gene Name
 CSH1 
Gene Synonyms/Alias
 YBR161W; YBR1212 
Created Date
 July 27, 2013 
Organism
 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) 
NCBI Taxa ID
 559292 
Lysine Modification
Position
Peptide
Type
References
166KVPAFLRKTSPTGVSubiquitination[1]
330WKLTSSYKNKEKRRNubiquitination[1]
371DIEKNHAKFTDLT**ubiquitination[1]
Reference
 [1] Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation.
 Swaney DL, Beltrao P, Starita L, Guo A, Rush J, Fields S, Krogan NJ, Villén J.
 Nat Methods. 2013 Jul;10(7):676-82. [PMID: 23749301] 
Functional Description
 Involved in the synthesis of mannosyl phosphorylinositol ceramide. Catalyzes the addition of mannosyl to phosphorylinositol ceramide. 
Sequence Annotation
 MOD_RES 354 354 Phosphoserine.  
Keyword
 Complete proteome; Membrane; Phosphoprotein; Reference proteome; Transferase; Transmembrane; Transmembrane helix; Vacuole. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 376 AA 
Protein Sequence
MKKELKILII ANIALLISII HYTFDLLTLC IDDTSKDALT DEQLNPPNGF NSTFYESPPQ 60
LIPKIIHQTY KTNDIPEQWV KGRQKCIDLH PDYTYILWTD EMSDTFIKQE YPWFLDTFRS 120
YEYPIERADA IRYFILSHYG GIYIDLDDGC ERRLDPLLKV PAFLRKTSPT GVSNDVMGSV 180
PRHPFFLKVI KSLKHYKKNW YIPYMTIMGS TGPLFISVVW KQYKRWSNTA ENGAVRILQP 240
ADYKMHNNSF FSISKGSSWH TGDANFMKTL ENHILSCVVT GFIFGFFILY GEFTFYTWLC 300
SGPFNNKRYY IQWLSDKFKL HKWKLTSSYK NKEKRRNPTR HEYNSRGKRL RKDSNIPYDS 360
VFLDIEKNHA KFTDLT 376 
Gene Ontology
 GO:0000324; C:fungal-type vacuole; IDA:SGD.
 GO:0016021; C:integral to membrane; ISM:SGD.
 GO:0005774; C:vacuolar membrane; IEA:UniProtKB-SubCell.
 GO:0000030; F:mannosyltransferase activity; IGI:SGD.
 GO:0006688; P:glycosphingolipid biosynthetic process; IMP:SGD. 
Interpro
 IPR007577; GlycoTrfase_DXD_sugar-bd_CS. 
Pfam
 PF04488; Gly_transf_sug 
SMART
  
PROSITE
  
PRINTS