UniProt Accession

 C9J9B4_HUMAN; C9J9B4 

Genbank Protein ID

 AC018904; AC091046 

Genbank Nucleotide ID

  

Protein Name

 Disintegrin and metalloproteinase domain-containing protein 10 

Protein Synonyms/Alias

  

Gene Name

 ADAM10 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Homo sapiens (Human) 

NCBI Taxa ID

 9606 

Lysine Modification

Position	Peptide	Type	References
45	NVDSLHQKHQRAKRA	ubiquitination	[1]

Reference

 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961] 

Functional Description

  

Sequence Annotation

  

Keyword

 Complete proteome; Reference proteome. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 125 AA 

Protein Sequence

Gene Ontology

 GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.
 GO:0008270; F:zinc ion binding; IEA:InterPro.
 GO:0006509; P:membrane protein ectodomain proteolysis; IEA:InterPro.
 GO:0007219; P:Notch signaling pathway; IEA:InterPro. 

Interpro

 IPR027053; ADAM_10.
 IPR002870; Peptidase_M12B_N. 

Pfam

 PF01562; Pep_M12B_propep 

SMART

  

PROSITE

  

PRINTS