CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-029902
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Protein Chd3 
Protein Synonyms/Alias
  
Gene Name
 Chd3 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
1119GKLLLLQKMLRKLKEacetylation[1]
Reference
 [1] Quantitative acetylome analysis reveals the roles of SIRT1 in regulating diverse substrates and cellular pathways.
 Chen Y, Zhao W, Yang JS, Cheng Z, Luo H, Lu Z, Tan M, Gu W, Zhao Y.
 Mol Cell Proteomics. 2012 Oct;11(10):1048-62. [PMID: 22826441] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Metal-binding; Nucleus; Reference proteome; Zinc; Zinc-finger. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 2055 AA 
Protein Sequence
MASPLRDEEE EEEEMVVSEE EEEEEEEGDE EEEEVEAADE DDEEEDEEGV LGRGPGHDRS 60
RDRHSPPSCH LFPPPPPPLP PPPPPDKDDI RLLPSALGVK KRKRGPKKQK ENKPGKPRKR 120
KKLDSEEEFG SERDEYREKS ESGGSEYGTG PGRKRRRKHR EKKEKKTKRR KRGEGDGGHK 180
QVEQKSSATL LLTWGLEDVE HVFSEEDYHT LTNYKAFSQF MRPLIAKKNP KIPMSKMMTI 240
LGAKWREFSA NNPFKGSAAA VAAAAAAAAA AVAEQVSAAV SSATPIAPSG PPPALPPPPA 300
PEIQPPPIRR AKTKEGKGPG HKRRNKSPRV PDGRKKLRGK KMAPLKIKLG LLGGKRKKAG 360
SCAFQSEEGH EPEAEESDLD SGSVHSASGW PDGPVRAKKL KRGRPGRKKK KVLGCPAVTG 420
EEEVDGYETD HQDYCEVCQQ GGEIILCDTC PRAYHLVCLD PELDRAPEGK WSCPHCEKEG 480
VQWEAKEEEE EYEEEGEEGE KEEEDDHMEY CRVCKDGGEL LCCDACISSY HIHCLNPPLP 540
DIPNGEWLCP RCTCPVLKGR VQKILHWRWG EPPVAVPAPQ QADGNPDVPP PRPLQGRSER 600
EFFVKWVGLS YWHCSWAKEL QLEIFHLVMY RNYQRKNDMD EPPPLDYGSG EDDGKSDKRK 660
VKDPHYAEME EKYYRFGIKP EWMTVHRIIN HSMDKKGNYH YLVKWKDLPY DQSTWEEDEM 720
NIPEYDDHKQ SYWRHRELIM GEDPAQPRKY KKKKKELQGD GPPSSPTNDP TVKYETQPRF 780
ITATGGTLHM YQLEGLNWLR FSWAQGTDTI LADEMGLGKT IQTIVFLYSL YKEGHTKGPF 840
LVSAPLSTII NWEREFQMWA PKFYVVTYTG DKDSRAIIRE NEFSFEDNAI KGGKKAFKMK 900
REAQVKFHVL LTSYELITID QAALGSIRWA CLVVDEAHRL KNNQSKFFRV LNGYKIDHKL 960
LLTGTPLQNN LEELFHLLNF LTPERFNNLE GFLEEFADIS KEDQIKKLHD LLGPHMLRRL 1020
KADVFKNMPA KTELIVRVEL SPMQKKYYKY ILTRNFEALN SRGGGNQVSL LNIMMDLKKC 1080
CNHPYLFPVA AMESPKLPSG AYEGGALIKS SGKLLLLQKM LRKLKEQGHR VLIFSQMTKM 1140
LDLLEDFLDY EGYKYERIDG GITGALRQEA IDRFNAPGAQ QFCFLLSTRA GGLGINLATA 1200
DTVIIFDSDW NPHNDIQAFS RAHRIGQANK VMIYRFVTRA SVEERITQVA KRKMMLTHLV 1260
VRPGLGSKAG SMSKQELDDI LKFGTEELFK DENEGENKEE DSSVIHYDNE AIARLLDRNQ 1320
DATEDTDVQN MNEYLSSFKV AQYVVREEDK IEEIEREIIK QEENVDPDYW EKLLRHHYEQ 1380
QQEDLARNLG KGKRVRKQVN YNDAAQEDQD NQSEYSVGSE EEDEDFDERP EGRRQSKRQL 1440
RNEKDKPLPP LLARVGGNIE VLGFNTRQRK AFLNAVMRWG MPPQDAFTTQ WLVRDLRGKT 1500
EKEFKAYVSL FMRHLCEPGA DGSETFADGV PREGLSRQQV LTRIGVMSLV KKKVQEFEHI 1560
NGRWSMPELM PDPSAESKRS SRASSPTKTS PTTPEASTTN SPCTSKPATP APSEKGDGVR 1620
TPLDKDDTEN QEEKPEKNSK VGEKMEAEVD SPSPAPSLGE RLEHRKILLE DEAPGVPGET 1680
EPEPGYRGDR EKSASEPTPG ERGEEKPLDV QEHRERTEGE TGDLGKREDV KADRELRLGP 1740
PRDEPRPNGR REEKVEKPRF MFNIADGGFT ELHTLWQNEE RAAISSGKLN EIWHRRHDYW 1800
LLAGIVLHGY ARWQDIQNDA QFAIINEPFK TEANKGNFLE MKNKFLARRF KLLEQALVIE 1860
EQLRRAAYLN LSQEPAHPAM ALHARFAEAE CLAESHQHLS KESLAGNKPA NAVLHKVLNQ 1920
LEELLSDMKA DVTRLPATLS RIPPIAARLQ MSERSILSRL ASKGTEPHPT PAFPPGPYAT 1980
PPGYGAAFSA APVGALAAAG ANYSQMPAGS FITATTNGPP VLVKKEKEMV GALVSDGLGL 2040
DRKEPRAGEV ICIDD 2055 
Gene Ontology
 GO:0045111; C:intermediate filament cytoskeleton; IEA:Compara.
 GO:0005730; C:nucleolus; IEA:Compara.
 GO:0016581; C:NuRD complex; IDA:MGI.
 GO:0005524; F:ATP binding; IEA:InterPro.
 GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.
 GO:0003677; F:DNA binding; IEA:InterPro.
 GO:0008270; F:zinc ion binding; IEA:InterPro.
 GO:0006333; P:chromatin assembly or disassembly; IDA:MGI.
 GO:0006355; P:regulation of transcription, DNA-dependent; IEA:InterPro. 
Interpro
 IPR012957; CHD_C2.
 IPR012958; CHD_N.
 IPR023780; Chromo_domain.
 IPR000953; Chromo_domain/shadow.
 IPR016197; Chromodomain-like.
 IPR002464; DNA/RNA_helicase_DEAH_CS.
 IPR009462; DUF1086.
 IPR009463; DUF1087.
 IPR014001; Helicase_ATP-bd.
 IPR001650; Helicase_C.
 IPR009071; HMG_box_dom.
 IPR027417; P-loop_NTPase.
 IPR000330; SNF2_N.
 IPR019786; Zinc_finger_PHD-type_CS.
 IPR011011; Znf_FYVE_PHD.
 IPR001965; Znf_PHD.
 IPR019787; Znf_PHD-finger.
 IPR001841; Znf_RING.
 IPR013083; Znf_RING/FYVE/PHD. 
Pfam
 PF08074; CHDCT2
 PF08073; CHDNT
 PF00385; Chromo
 PF06461; DUF1086
 PF06465; DUF1087
 PF00271; Helicase_C
 PF00628; PHD
 PF00176; SNF2_N 
SMART
 SM00298; CHROMO
 SM00487; DEXDc
 SM00490; HELICc
 SM00249; PHD
 SM00184; RING 
PROSITE
 PS50013; CHROMO_2
 PS00690; DEAH_ATP_HELICASE
 PS51192; HELICASE_ATP_BIND_1
 PS51194; HELICASE_CTER
 PS01359; ZF_PHD_1
 PS50016; ZF_PHD_2 
PRINTS