CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-039550
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Phosphatidylinositol transfer protein alpha isoform 
Protein Synonyms/Alias
  
Gene Name
 PITPNA 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
50LVNEPYEKDGEKGQYubiquitination[1]
86GALNIHEKAWNAYPYubiquitination[2, 3]
152DRSQVLSKDYKAEEDubiquitination[2, 4]
162KAEEDPAKFKSIKTGubiquitination[2]
178GPLGPNWKQELVNQKubiquitination[1, 2]
201KLVTVKFKWWGLQNKubiquitination[2]
208KWWGLQNKVENFIHKubiquitination[2, 4]
215KVENFIHKQERRLFTubiquitination[4]
Reference
 [1] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983]
 [2] A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles.
 Wagner SA, Beli P, Weinert BT, Nielsen ML, Cox J, Mann M, Choudhary C.
 Mol Cell Proteomics. 2011 Oct;10(10):M111.013284. [PMID: 21890473]
 [3] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961]
 [4] Systems-wide analysis of ubiquitylation dynamics reveals a key role for PAF15 ubiquitylation in DNA-damage bypass.
 Povlsen LK, Beli P, Wagner SA, Poulsen SL, Sylvestersen KB, Poulsen JW, Nielsen ML, Bekker-Jensen S, Mailand N, Choudhary C.
 Nat Cell Biol. 2012 Oct;14(10):1089-98. [PMID: 23000965
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 270 AA 
Protein Sequence
MVLLKEYRVI LPVSVDEYQV GQLYSVAEAS KNETGGGEGV EVLVNEPYEK DGEKGQYTHK 60
IYHLQSKVPT FVRMLAPEGA LNIHEKAWNA YPYCRTVLPN EYMKEDFLIK IETWHKPDLG 120
TQENVHKLEP EAWKHVEAVY IDIADRSQVL SKDYKAEEDP AKFKSIKTGR GPLGPNWKQE 180
LVNQKDCPYM CAYKLVTVKF KWWGLQNKVE NFIHKQERRL FTNFHRQLFC WLDKWVDLTM 240
DDIRRMEEET KRQLDEMRQK DPVKGMTADD 270 
Gene Ontology
 GO:0005622; C:intracellular; IEA:InterPro.
 GO:0006810; P:transport; IEA:InterPro. 
Interpro
 IPR001666; PI_transfer.
 IPR023393; START-like_dom. 
Pfam
 PF02121; IP_trans 
SMART
  
PROSITE
  
PRINTS
 PR00391; PITRANSFER.