CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-029803
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Metal-response element-binding transcription factor 2 
Protein Synonyms/Alias
  
Gene Name
 MTF2 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
161CVFATTTKRGGALKKubiquitination[1]
313GELADTPKSERYEHVubiquitination[1, 2]
Reference
 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961]
 [2] Integrated proteomic analysis of post-translational modifications by serial enrichment.
 Mertins P, Qiao JW, Patel J, Udeshi ND, Clauser KR, Mani DR, Burgess MW, Gillette MA, Jaffe JD, Carr SA.
 Nat Methods. 2013 Jul;10(7):634-7. [PMID: 23749302] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Metal-binding; Reference proteome; Zinc; Zinc-finger. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 536 AA 
Protein Sequence
MRDSTGAGNS LVHKRSPLRR NQKTPTSLTK LSLQDGHKAK KPACKFEEGQ DVLARWSDGL 60
FYLGTIKKIN ILKQSCFIIF EDSSKSWVLW KDIQTGATGS GEMVCTICQE EYSEAPNEMV 120
ICDKCGQGYH QLCHTPHIDC SVIDSDEKWL CRQCVFATTT KRGGALKKGP NAKALQVMKQ 180
TLPYSVADLE WDAGHKTNVQ QCYCYCGGPG DWYLKMLQCC KCKQWFHEAC VQCLQKPMLF 240
GDRFYTFICS VCSSGPEYLK RLPLQWVDIA HLCLYNLSVI HKKKYFDSEL ELMTYINENW 300
DRLHPGELAD TPKSERYEHV LEALNDYKTM EVSNGIEKKG KKKSVGRPPG PYTRKMIQKT 360
AEPLLDKESI SENPTLDLPC SIGRTEGTAH SSNTSDVDFT GASSAKETTS SSISRHYGLS 420
DSRKRTRTGR SWPAAIPHLR RRRGRLPRRA LQTQNSEIVK DDEGKEDYQF DELNTEILNN 480
LADQELQLNH LKNSITSYFG AAGRIACGEK YRVLARRVTL DGKVQYLVEW EGATAS 536 
Gene Ontology
 GO:0008270; F:zinc ion binding; IEA:InterPro. 
Interpro
 IPR025894; Mtf2_C_dom.
 IPR002999; Tudor.
 IPR019786; Zinc_finger_PHD-type_CS.
 IPR011011; Znf_FYVE_PHD.
 IPR001965; Znf_PHD.
 IPR019787; Znf_PHD-finger.
 IPR013083; Znf_RING/FYVE/PHD. 
Pfam
 PF14061; Mtf2_C
 PF00628; PHD 
SMART
 SM00249; PHD
 SM00333; TUDOR 
PROSITE
 PS01359; ZF_PHD_1
 PS50016; ZF_PHD_2 
PRINTS