CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-039848
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 mRNA cap guanine-N7 methyltransferase 
Protein Synonyms/Alias
  
Gene Name
 RNMT 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
186YPANESSKLVSEKVDubiquitination[1]
191SSKLVSEKVDDYEHAacetylation[2]
191SSKLVSEKVDDYEHAubiquitination[3]
203EHAAKYMKNSQVRLPubiquitination[3]
Reference
 [1] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983]
 [2] Integrated proteomic analysis of post-translational modifications by serial enrichment.
 Mertins P, Qiao JW, Patel J, Udeshi ND, Clauser KR, Mani DR, Burgess MW, Gillette MA, Jaffe JD, Carr SA.
 Nat Methods. 2013 Jul;10(7):634-7. [PMID: 23749302]
 [3] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 234 AA 
Protein Sequence
MKNRRDSEYI FSAEFITADS SKELLIDKFR DPQMCFDICS CQFVCHYSFE SYEQADMMLR 60
NACERLSPGG YFIGTTPNSF ELIRRLEASE TESFGNEIYT VKFQKKGDYP LFGCKYDFNL 120
EGVVDVPEFL VYFPLLNEMA KKYNMKLVYK KTFLEFYEEK IKNNENKMLL KRMQALEPYP 180
ANESSKLVSE KVDDYEHAAK YMKNSQVRLP LGTLSKSEWE ATSIYLVFAF EKQQ 234 
Gene Ontology
  
Interpro
 IPR004971; mRNA_G-N7_MeTrfase_dom. 
Pfam
 PF03291; Pox_MCEL 
SMART
  
PROSITE
 PS51562; RNA_CAP0_MT 
PRINTS