CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-018949
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Gamma-tubulin complex component 5 
Protein Synonyms/Alias
 GCP-5 
Gene Name
 TUBGCP5 
Gene Synonyms/Alias
 GCP5; QtsA-11379 
Created Date
 July 27, 2013 
Organism
 Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey) 
NCBI Taxa ID
 9541 
Lysine Modification
Position
Peptide
Type
References
254HTMVSFLKPVLKQIIubiquitination[1]
265KQIIMAGKSMQLLKNubiquitination[1]
271GKSMQLLKNLQCAESubiquitination[1]
291GARDAERKSLYTLFLubiquitination[1]
398CLYPHIDKQYLDCCGubiquitination[1]
490ENVDTAKKKLPVHILubiquitination[1]
Reference
 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961] 
Functional Description
 Gamma-tubulin complex is necessary for microtubule nucleation at the centrosome (By similarity). 
Sequence Annotation
  
Keyword
 Cytoplasm; Cytoskeleton; Microtubule. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 725 AA 
Protein Sequence
IIVTHLTHSC LRSVLEQIAA YGQVVFRLQQ FIDEVMGHSS ESMLPGSGSV PKKSTEAPFR 60
TYQAFMWALY KYFISSKEEL AEIEKCIINN DATITLAIVV DKLAPRLAQL KVLHKVFSTG 120
VAEVPPDTRN VVRASHLLNT LYKAILEYDD VGEASEQTVS LLFSLWVETV RPYLQTVDEW 180
IVHGHLWDGA REFIIQRNKN VPVNHRDFWY ATYTLYSVSE KTENEEKMSD NASASSGSDQ 240
GPSSRQHTMV SFLKPVLKQI IMAGKSMQLL KNLQCAESTT CQAGARDAER KSLYTLFLES 300
VQSRLRHGED STPQVLTEQQ ATKENLMKMQ SIAERHLELD DVHDPLLAIN FARMYLEQSD 360
FHEKFAGGDV CVDRSSESVT CQTFELTLRS CLYPHIDKQY LDCCGNLMQT LKKDYRLVEY 420
LQAMRNFFLM EGGDTMYDFY TSIFDKIREK ETWQNVSFLN VQLQEAVGQR YPEDSSRLSI 480
SFENVDTAKK KLPVHILDGL TLSYKVPWPV DIVISLECQK IYNQVFLLLL QIKWAKYSLD 540
VLLFGELVST AEKPRLQEGL VREQDTVAQF GPQKEPVRQQ IHRMFLLRVK LMHFVNSLHN 600
YIMTRILHST GLEFQHQVEE AKDLDQLIKI HYRYLSTIHD RCLLREKVSF VKEAIMKVLN 660
LALMFADGWQ AGLGTWRMES IEKMESDFKN CHMFLVTILN KAVCRGSFPH LESLALSLMA 720
GMEQS 725 
Gene Ontology
 GO:0008274; C:gamma-tubulin ring complex; ISS:UniProtKB.
 GO:0005874; C:microtubule; IEA:UniProtKB-KW.
 GO:0000922; C:spindle pole; IEA:InterPro.
 GO:0008017; F:microtubule binding; ISS:UniProtKB.
 GO:0007020; P:microtubule nucleation; ISS:UniProtKB. 
Interpro
 IPR007259; Spc97_Spc98. 
Pfam
 PF04130; Spc97_Spc98 
SMART
  
PROSITE
  
PRINTS