CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-019492
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Zinc finger protein 570 
Protein Synonyms/Alias
  
Gene Name
 ZNF570 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
81MVKRELTKGLCSGWEubiquitination[1]
99ETEELTPKQDFYEEHubiquitination[1]
Reference
 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961
Functional Description
 May be involved in transcriptional regulation. 
Sequence Annotation
 DOMAIN 14 85 KRAB.
 ZN_FING 218 240 C2H2-type 1.
 ZN_FING 246 268 C2H2-type 2.
 ZN_FING 274 296 C2H2-type 3.
 ZN_FING 302 324 C2H2-type 4.
 ZN_FING 330 352 C2H2-type 5.
 ZN_FING 358 380 C2H2-type 6.
 ZN_FING 386 408 C2H2-type 7.
 ZN_FING 414 436 C2H2-type 8.
 ZN_FING 442 464 C2H2-type 9.
 ZN_FING 470 492 C2H2-type 10.
 ZN_FING 498 520 C2H2-type 11.  
Keyword
 Complete proteome; DNA-binding; Metal-binding; Nucleus; Reference proteome; Repeat; Transcription; Transcription regulation; Zinc; Zinc-finger. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 536 AA 
Protein Sequence
MAVGLLKAMY QELVTFRDVA VDFSQEEWDC LDSSQRHLYS NVMLENYRIL VSLGLCFSKP 60
SVILLLEQGK APWMVKRELT KGLCSGWEPI CETEELTPKQ DFYEEHQSQK IIETLTSYNL 120
EYSSLREEWK CEGYFERQPG NQKACFKEEI ITHEEPLFDE REQEYKSWGS FHQNPLLCTQ 180
KIIPKEEKVH KHDTQKRSFK KNLMAIKPKS VCAEKKLLKC NDCEKVFSQS SSLTLHQRIH 240
TGEKPYKCIE CGKAFSQRSN LVQHQRIHTG EKPYECKECR KAFSQNAHLV QHLRVHTGEK 300
PYECKVCRKA FSQFAYLAQH QRVHTGEKPY ECIECGKAFS NRSSIAQHQR VHTGEKPYEC 360
NVCGKAFSLR AYLTVHQRIH TGERPYECKE CGKAFSQNSH LAQHQRIHTG EKPYKCQECR 420
KAFSQIAYLA QHQRVHTGEK PYECIECGKA FSNDSSLTQH QRVHTGEKPY ECTVCGKAFS 480
YCGSLAQHQR IHTGERPYEC KECKKTFRQH AHLAHHQRIH IGESLSPPNP VNHQVL 536 
Gene Ontology
 GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
 GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
 GO:0008270; F:zinc ion binding; IEA:InterPro.
 GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.
 GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. 
Interpro
 IPR001909; Krueppel-associated_box.
 IPR007087; Znf_C2H2.
 IPR015880; Znf_C2H2-like.
 IPR013087; Znf_C2H2/integrase_DNA-bd. 
Pfam
 PF01352; KRAB 
SMART
 SM00349; KRAB
 SM00355; ZnF_C2H2 
PROSITE
 PS50805; KRAB
 PS00028; ZINC_FINGER_C2H2_1
 PS50157; ZINC_FINGER_C2H2_2 
PRINTS