CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-039883
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Poly [ADP-ribose] polymerase 6 
Protein Synonyms/Alias
  
Gene Name
 PARP6 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
384KNYERLQKALDSVMSubiquitination[1]
Reference
 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 553 AA 
Protein Sequence
MDIKGQFWND DDSEGDNESE EFLYGVQGSC AADLYRHPQL DADIEAVKEI YSENSVSIRE 60
YGTIDDVDID LHINISFLDE EVSTAWKVLR TEPIVLRLRF SLSQYLDGPE PSIEVFQPSN 120
KEGFGLGLQL KKILGMFTSQ QWKHLSNDFL KTQQEKRHSW FKASGTIKKF RAGLSIFSPI 180
PKSPSFPIIQ DSMLKGKLGV PELRVGRLMN RSISCTMKNP KVEVFGYPPS PQAGLLCPQH 240
VGLPPPARTS PLVSGHCKNI PTLEYGFLVQ IMKYAEQRIP TLNEYCVVCD EQHVFQNGSM 300
LKPAVCTREL CVFSFYTLGV MSGAAEEVAT GAEVVDLLVA MCRAALESPR KSIIFEPYPS 360
VVDPTDPKTL AFNPKKKNYE RLQKALDSVM SIREMTQGSY LEIKKQMDKL DPLAHPLLQW 420
IISSNRSHIV KLPLSRQLKF MHTSHQFLLL SSPPAKEARF RTAKKLYGST FAFHGSHIEN 480
WHSILRNGLV NASYTKLQLH GAAYGKGIYL SPISSISFGY SGMGKGQHRM PSKDELVQRY 540
NRMNTIPQTR SIQ 553 
Gene Ontology
 GO:0003950; F:NAD+ ADP-ribosyltransferase activity; IEA:InterPro. 
Interpro
 IPR012317; Poly(ADP-ribose)pol_cat_dom. 
Pfam
 PF00644; PARP 
SMART
  
PROSITE
 PS51059; PARP_CATALYTIC 
PRINTS