CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-044246
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Mixed lineage kinase domain-like protein 
Protein Synonyms/Alias
  
Gene Name
 MLKL 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
155EAPELHGKIRSSNFLubiquitination[1]
Reference
 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 175 AA 
Protein Sequence
XSDLPPKCMQ EIPQEQIKEI KKEQLSGSPW ILLRENEVST LYKGEYHRAP VAIKVFKKLQ 60
AGSIAIVRQT FNKEIKTMKK FESPNILRIF GICIDETVTP PQFSIVMEYC ELGTLRELLD 120
REKDLTLGKR MVLVLGAARG LYRLHHSEAP ELHGKIRSSN FLVTQGYQVK IWVPG 175 
Gene Ontology
 GO:0005524; F:ATP binding; IEA:InterPro.
 GO:0004672; F:protein kinase activity; IEA:InterPro. 
Interpro
 IPR011009; Kinase-like_dom.
 IPR000719; Prot_kinase_cat_dom.
 IPR001245; Ser-Thr/Tyr_kinase_cat_dom. 
Pfam
 PF07714; Pkinase_Tyr 
SMART
  
PROSITE
 PS50011; PROTEIN_KINASE_DOM 
PRINTS