CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-025154
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Pleckstrin homology domain containing, family C (With FERM domain) member 1 
Protein Synonyms/Alias
  
Gene Name
 Fermt2 
Gene Synonyms/Alias
 Plekhc1; mCG_2018 
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
247QALLDKAKTNQGWLDubiquitination[1]
265SLMEQDVKENEALLLubiquitination[1]
275EALLLRFKYYSFFDLubiquitination[1]
285SFFDLNPKYDAIRINubiquitination[1]
555QMSLIEAKMRFIQAWubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 
Functional Description
  
Sequence Annotation
  
Keyword
  
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 680 AA 
Protein Sequence
MALDGIRMPD GCYADGTWEL SVHVTDLNRD VTLRVTGEVH IGGVMLKLVE KLDVKKDWSD 60
HALWWEKKRT WLLKTHWTLD KCGIQADAKL QFTPQHKLLR LQLPNMKYVK VKVNFSDRVF 120
KAVSDICKTF NIRHPEELSL LKKPRDPTKK KKKKLDDQSE DEALELEGPL IMPGSGSIYS 180
SPGLYSKTMT PTYDAHDGSP LSPTSAWFGD SALSEGNPGI LAVSQPVTSP EILAKMFKPQ 240
ALLDKAKTNQ GWLDSSRSLM EQDVKENEAL LLRFKYYSFF DLNPKYDAIR INQLYEQAKW 300
ALLLEEIECT EEEMMMFAAL QYHINKLSIM TSENHLNNSD KEVDEVDAAL SDLEITLEGG 360
KTSTILGDIT SIPELADYIK VFKPKKLTLK GYKQYWCTFK DTSISCYKSR EESSGTPAHQ 420
LNLRGCEVTP DVNISGQKFN IKLLIPVAEG MNEIWLRCDN EKQYAHWMAA CRLASKGKTM 480
ADSSYNLEVQ NILSFLKMQH LNPDPQLIPD QITTDVNPEC LVSPRYLKKY KSKQITARIL 540
EAHQNVAQMS LIEAKMRFIQ AWQSLPEFGI THFIARFQGG KREELIGIAY NRLIRMDAST 600
GDAIKTWRFS NMKQWNVNWE IKMVTVEFAD EVRLSFICTE VDCKVVHEFI GGYIFLSTRA 660
KDQNESLDEE MFYKLTSGWV 680 
Gene Ontology
 GO:0005925; C:focal adhesion; IEA:Compara.
 GO:0005634; C:nucleus; IEA:Compara.
 GO:0005543; F:phospholipid binding; IEA:InterPro. 
Interpro
 IPR019749; Band_41_domain.
 IPR014352; FERM/acyl-CoA-bd_prot_3-hlx.
 IPR019748; FERM_central.
 IPR018979; FERM_N.
 IPR011993; PH_like_dom.
 IPR001849; Pleckstrin_homology. 
Pfam
 PF00373; FERM_M
 PF09379; FERM_N
 PF00169; PH 
SMART
 SM00295; B41
 SM00233; PH 
PROSITE
 PS50003; PH_DOMAIN 
PRINTS