| Tag | Content |
|---|
| CPLM ID | CPLM-007771 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Solute carrier family 15 member 1 |
Protein Synonyms/Alias | Intestinal H(+)/peptide cotransporter; Oligopeptide transporter, small intestine isoform; Peptide transporter 1 |
Gene Name | SLC15A1 |
Gene Synonyms/Alias | PEPT1 |
Created Date | July 27, 2013 |
Organism | Homo sapiens (Human) |
NCBI Taxa ID | 9606 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 474 | PNHYQVVKDGLNQKP | acetylation | [1] |
|
Reference | [1] Regulation of cellular metabolism by protein lysine acetylation. Zhao S, Xu W, Jiang W, Yu W, Lin Y, Zhang T, Yao J, Zhou L, Zeng Y, Li H, Li Y, Shi J, An W, Hancock SM, He F, Qin L, Chin J, Yang P, Chen X, Lei Q, Xiong Y, Guan KL. Science. 2010 Feb 19;327(5968):1000-4. [ PMID: 20167786] |
Functional Description | Proton-coupled intake of oligopeptides of 2 to 4 amino acids with a preference for dipeptides. May constitute a major route for the absorption of protein digestion end-products. |
Sequence Annotation | CARBOHYD 50 50 N-linked (GlcNAc...) (Potential).
CARBOHYD 404 404 N-linked (GlcNAc...) (Potential).
CARBOHYD 408 408 N-linked (GlcNAc...) (Potential).
CARBOHYD 439 439 N-linked (GlcNAc...) (Potential).
CARBOHYD 509 509 N-linked (GlcNAc...) (Potential).
CARBOHYD 514 514 N-linked (GlcNAc...) (Potential).
CARBOHYD 562 562 N-linked (GlcNAc...) (Potential). |
Keyword | Complete proteome; Glycoprotein; Membrane; Peptide transport; Polymorphism; Protein transport; Reference proteome; Symport; Transmembrane; Transmembrane helix; Transport. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 708 AA |
Protein Sequence | MGMSKSHSFF GYPLSIFFIV VNEFCERFSY YGMRAILILY FTNFISWDDN LSTAIYHTFV 60
ALCYLTPILG ALIADSWLGK FKTIVSLSIV YTIGQAVTSV SSINDLTDHN HDGTPDSLPV 120
HVVLSLIGLA LIALGTGGIK PCVSAFGGDQ FEEGQEKQRN RFFSIFYLAI NAGSLLSTII 180
TPMLRVQQCG IHSKQACYPL AFGVPAALMA VALIVFVLGS GMYKKFKPQG NIMGKVAKCI 240
GFAIKNRFRH RSKAFPKREH WLDWAKEKYD ERLISQIKMV TRVMFLYIPL PMFWALFDQQ 300
GSRWTLQATT MSGKIGALEI QPDQMQTVNA ILIVIMVPIF DAVLYPLIAK CGFNFTSLKK 360
MAVGMVLASM AFVVAAIVQV EIDKTLPVFP KGNEVQIKVL NIGNNTMNIS LPGEMVTLGP 420
MSQTNAFMTF DVNKLTRINI SSPGSPVTAV TDDFKQGQRH TLLVWAPNHY QVVKDGLNQK 480
PEKGENGIRF VNTFNELITI TMSGKVYANI SSYNASTYQF FPSGIKGFTI SSTEIPPQCQ 540
PNFNTFYLEF GSAYTYIVQR KNDSCPEVKV FEDISANTVN MALQIPQYFL LTCGEVVFSV 600
TGLEFSYSQA PSNMKSVLQA GWLLTVAVGN IIVLIVAGAG QFSKQWAEYI LFAALLLVVC 660
VIFAIMARFY TYINPAEIEA QFDEDEKKNR LEKSNPYFMS GANSQKQM 708 |
Gene Ontology | GO:0005887; C:integral to plasma membrane; TAS:ProtInc. GO:0015333; F:peptide:hydrogen symporter activity; TAS:ProtInc. GO:0005427; F:proton-dependent oligopeptide secondary active transmembrane transporter activity; IEA:Compara. GO:0007586; P:digestion; TAS:ProtInc. GO:0015031; P:protein transport; IEA:UniProtKB-KW. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |