CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-038184
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Protein Cyp2c69 
Protein Synonyms/Alias
  
Gene Name
 Cyp2c69 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
105GSFPFFDKVSKGKGIubiquitination[1]
190FQNRFDYKDKDFLSLubiquitination[1]
192NRFDYKDKDFLSLIGubiquitination[1]
235GRHNKFFKNHTWIKSubiquitination[1]
241FKNHTWIKSYLLEKIubiquitination[1]
247IKSYLLEKIKEHEESubiquitination[1]
249SYLLEKIKEHEESLDubiquitination[1]
322KHTHITAKVQEEIDNubiquitination[1]
375HEVTCDTKFRNYFIPubiquitination[1]
421DDNGNFKKSDYFVPFubiquitination[1]
432FVPFSAGKRICVGESubiquitination[1]
459ILQNFKLKPLVDPKDubiquitination[1]
472KDIDTTPKYSGFSKIubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Heme; Iron; Metal-binding; Monooxygenase; Oxidoreductase; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 491 AA 
Protein Sequence
MDPFVVLVLC LSFMLLLSLW RQRSARRNLP PGPTPLPIIG NYHLIDMKDI GQCLTNFSKT 60
YGPVFTLYFG SQPIVVLHGY EAIKEALIDH GEVFSGRGSF PFFDKVSKGK GIGFSHGNVW 120
KATRVFTVNT LRNLAMGKRT IENKVQEEAQ WLMKELKKTN GSPCDPQFII GCAPCNVICS 180
IVFQNRFDYK DKDFLSLIGK VNECTEILSS PGCQIFNAVP ILIDYCPGRH NKFFKNHTWI 240
KSYLLEKIKE HEESLDVTNP RDFIDYFLIQ RRQDKGIEHM EYTIEHLATL VTDLVFGGTE 300
TLSSTMRFAL LLLMKHTHIT AKVQEEIDNV IGRHRSPCMQ DRKHMPYTNA MVHEVQRYVD 360
LGPTSLVHEV TCDTKFRNYF IPKGTQVMTS LSSVLHDSTE FPNPEVFDPG HFLDDNGNFK 420
KSDYFVPFSA GKRICVGESL ARMELFLFLT TILQNFKLKP LVDPKDIDTT PKYSGFSKIP 480
PKFQMCFIPV E 491 
Gene Ontology
 GO:0009055; F:electron carrier activity; IEA:InterPro.
 GO:0020037; F:heme binding; IEA:InterPro.
 GO:0005506; F:iron ion binding; IEA:InterPro.
 GO:0004497; F:monooxygenase activity; IEA:UniProtKB-KW.
 GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro. 
Interpro
 IPR001128; Cyt_P450.
 IPR017972; Cyt_P450_CS.
 IPR002401; Cyt_P450_E_grp-I. 
Pfam
 PF00067; p450 
SMART
  
PROSITE
 PS00086; CYTOCHROME_P450 
PRINTS
 PR00463; EP450I.
 PR00385; P450.