| Tag | Content |
|---|
| CPLM ID | CPLM-017051 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Probable ATP-dependent RNA helicase DHX40 |
Protein Synonyms/Alias | DEAH box protein 40; Protein PAD |
Gene Name | DHX40 |
Gene Synonyms/Alias | DDX40; ARG147 |
Created Date | July 27, 2013 |
Organism | Homo sapiens (Human) |
NCBI Taxa ID | 9606 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 340 | LEVVPISKSEALQRS | ubiquitination | [1] |
|
Reference | [1] Landscape of the PARKIN-dependent ubiquitylome in response to mitochondrial depolarization. Sarraf SA, Raman M, Guarani-Pereira V, Sowa ME, Huttlin EL, Gygi SP, Harper JW. Nature. 2013 Apr 18;496(7445):372-6. [ PMID: 23503661] |
Functional Description | Probable ATP-dependent RNA helicase (By similarity). |
Sequence Annotation | DOMAIN 63 231 Helicase ATP-binding.
DOMAIN 263 442 Helicase C-terminal.
NP_BIND 76 83 ATP (By similarity).
MOTIF 173 176 DEAH box. |
Keyword | Alternative splicing; ATP-binding; Complete proteome; Helicase; Hydrolase; Nucleotide-binding; Reference proteome. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 779 AA |
Protein Sequence | MIGVTQPRKV AAISVAQRVA EEMKCTLGSK VGYQVRFDDC SSKETAIKYM TDGCLLKHIL 60
GDPNLTKFSV IILDEAHERT LTTDILFGLL KKLFQEKSPN RKEHLKVVVM SATMELAKLS 120
AFFGNCPIFD IPGRLYPVRE KFCNLIGPRD RENTAYIQAI VKVTMDIHLN EMAGDILVFL 180
TGQFEIEKSC ELLFQMAESV DYDYDVQDTT LDGLLILPCY GSMTTDQQRR IFLPPPPGIR 240
KCVISTNISA TSLTIDGIRY VVDGGFVKQL NHNPRLGLEQ RRIFLPPPPG IRKCVISTNI 300
SATSLTIDGI RYVVDGGFVK QLNHNPRLGL DILEVVPISK SEALQRSGRA GRTSSGKCFR 360
IYSKDFWNQC MPDHVIPEIK RTSLTSVVLT LKCLAIHDVI RFPYLDPPNE RLILEALKQL 420
YQCDAIDRSG HVTRLGLSMV EFPLPPHLTC AVIKAASLDC EDLLLPIAAM LSVENVFIRP 480
VDPEYQKEAE QRHRELAAKA GGFNDFATLA VIFEQCKSSG APASWCQKHW IHWRCLFSAF 540
RVEAQLRELI RKLKQQSDFP KETFEGPKHE VLRRCLCAGY FKNVARRSVG RTFCTMDGRG 600
SPVHIHPSSA LHEQETKLEW IIFHEVLVTT KVYARIVCPI RYEWVRDLLP KLHEFNAHDL 660
SSVARREVRE DARRRWTNKE NVKQLKDGIS KDVLKKMQRR NDDKSISDAR ARFLERKQQR 720
TQDHSDTRKE TG 732 |
Gene Ontology | GO:0005524; F:ATP binding; IEA:UniProtKB-KW. GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro. GO:0003676; F:nucleic acid binding; IEA:InterPro. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |