CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-036857
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Histone-lysine N-methyltransferase 
Protein Synonyms/Alias
  
Gene Name
 SETMAR 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
498LNNFLQGKRFHNQQDubiquitination[1]
535QLISRWQKCVDCNGSubiquitination[1]
Reference
 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 545 AA 
Protein Sequence
MFAEAAKTTR PCGMAEFKEK PEAPTEQLDV ACGQENLPVG AWPPGAAPAP FQYTPDHVVG 60
PGADIDPTQI TFPGCICVKT PCLPGTCSCL RHGENYDDNS CLRDIGSGGK YAEPVFECNV 120
LCRCSDHCRN RVVQKGLQFH FQVFKTHKKG WGLRTLEFIP KGSSLYCPVE KSNISCGNEK 180
EPSMCGSAPS VFPSCKRLTL ETMKMMLDKK QIRAIFLFEF KMGRKAAETT RNINNAFGPG 240
TANERTVQWW FKKFCKGDES LEDEERSGRP SEVDNDQLRA IIEADPLTTT REVAEELNVN 300
HSTVVRHLKQ IGKVKKLDKW VPHELTENQK NRRFEVSSSL ILRNHNEPFL DRIVTCDEKW 360
ILYDNRRRSA QWLDQEEAPK HFPKPILHPK KVMVTIWWSA AGLIHYSFLN PGETITSEKY 420
AQEIDEMNQK LQRLQLALVN RKGPILLHDN ARPHVAQPTL QKLNELGYEV LPHPPYSPDL 480
LPTNYHVFKH LNNFLQGKRF HNQQDAENAF QEFVESQSTD FYATGINQLI SRWQKCVDCN 540
GSYFD 545 
Gene Ontology
 GO:0005634; C:nucleus; IEA:InterPro.
 GO:0003677; F:DNA binding; IEA:InterPro.
 GO:0018024; F:histone-lysine N-methyltransferase activity; IEA:InterPro.
 GO:0004803; F:transposase activity; IEA:InterPro.
 GO:0008270; F:zinc ion binding; IEA:InterPro.
 GO:0015074; P:DNA integration; IEA:InterPro.
 GO:0006313; P:transposition, DNA-mediated; IEA:InterPro. 
Interpro
 IPR007728; Pre-SET_dom.
 IPR003606; Pre-SET_Zn-bd_sub.
 IPR001888; Transposase_1.
 IPR002492; Transposase_Tc1-like. 
Pfam
 PF01498; HTH_Tnp_Tc3_2
 PF05033; Pre-SET
 PF01359; Transposase_1 
SMART
 SM00468; PreSET 
PROSITE
 PS50867; PRE_SET 
PRINTS