UniProt Accession

 NDK_RHOPA; Q6N5C3 

Genbank Protein ID

 BX572602 

Genbank Nucleotide ID

 CAE28497.1 

Protein Name

 Nucleoside diphosphate kinase 

Protein Synonyms/Alias

 NDK; NDP kinase; Nucleoside-2-P kinase 

Gene Name

 ndk 

Gene Synonyms/Alias

 RPA3056 

Created Date

 July 27, 2013 

Organism

 Rhodopseudomonas palustris (strain ATCC BAA-98 / CGA009) 

NCBI Taxa ID

 258594 

Lysine Modification

Position	Peptide	Type	References
29	AINALIEKAGLRIVA	acetylation	[1]
97	MGATDPSKAADGTIR	acetylation	[1]

Reference

 [1] System-wide studies of N-lysine acetylation in Rhodopseudomonas palustris reveal substrate specificity of protein acetyltransferases.
 Crosby HA, Pelletier DA, Hurst GB, Escalante-Semerena JC.
 J Biol Chem. 2012 May 4;287(19):15590-601. [PMID: 22416131] 

Functional Description

 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity). 

Sequence Annotation

 ACT_SITE 117 117 Pros-phosphohistidine intermediate (By
 BINDING 11 11 ATP (By similarity).
 BINDING 59 59 ATP (By similarity).
 BINDING 87 87 ATP (By similarity).
 BINDING 93 93 ATP (By similarity).
 BINDING 104 104 ATP (By similarity).
 BINDING 114 114 ATP (By similarity).  

Keyword

 ATP-binding; Complete proteome; Cytoplasm; Kinase; Magnesium; Metal-binding; Nucleotide metabolism; Nucleotide-binding; Phosphoprotein; Transferase. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 140 AA 

Protein Sequence

Gene Ontology

 GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
 GO:0005524; F:ATP binding; IEA:HAMAP.
 GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
 GO:0004550; F:nucleoside diphosphate kinase activity; IEA:HAMAP.
 GO:0006241; P:CTP biosynthetic process; IEA:HAMAP.
 GO:0006183; P:GTP biosynthetic process; IEA:HAMAP.
 GO:0006228; P:UTP biosynthetic process; IEA:HAMAP. 

Interpro

 IPR001564; Nucleoside_diP_kinase. 

Pfam

 PF00334; NDK 

SMART

 SM00562; NDK 

PROSITE

 PS00469; NDP_KINASES 

PRINTS

 PR01243; NUCDPKINASE.