CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-017642
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Coiled-coil domain-containing protein 168 
Protein Synonyms/Alias
  
Gene Name
 CCDC168 
Gene Synonyms/Alias
 C13orf40 
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
357QDSSDSGKKAYTESLubiquitination[1, 2]
358DSSDSGKKAYTESLHubiquitination[1, 2]
429KSKEQKRKIQEDKNKubiquitination[3]
518KEEKDREKVADMTSVubiquitination[2]
530TSVLDPNKMYLKAKKubiquitination[2]
782NIGGQGRKEHEGQDKubiquitination[2]
1182PQTKGSLKKISIVTNubiquitination[2]
1183QTKGSLKKISIVTNWubiquitination[2]
2220HCTRECRKETLIITPubiquitination[2]
Reference
 [1] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983]
 [2] Landscape of the PARKIN-dependent ubiquitylome in response to mitochondrial depolarization.
 Sarraf SA, Raman M, Guarani-Pereira V, Sowa ME, Huttlin EL, Gygi SP, Harper JW.
 Nature. 2013 Apr 18;496(7445):372-6. [PMID: 23503661]
 [3] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961
Functional Description
  
Sequence Annotation
  
Keyword
 Coiled coil; Complete proteome; Polymorphism; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 2452 AA 
Protein Sequence
MAQIQKDKAN ISEKSVMHPE YIAVKAEKSP LSHILKTKEL QVNISQQGEK AQEGEVEIVV 60
LLSKTCPFVT SSAFLELDSI KEEEGEPRIT RSFMPHLEIQ ESLPSRQTAP TKPTESLVKK 120
EKQLLPQKED RVQTVSMHGL MHPNGAVFKA KTSAPPQVFS ITEHSPLSKR KEPQWGMKER 180
AGQKQDRTGR PHVILTKTHP FMPSLSHHRF SPSQPKLPIS SGAGKSRLAN SNEGISSHKV 240
ILKANQQMPY KEAKDRVKIE GREGRILPKR IHLRAEALPL ALLCNGKNYS LHIEEQGEGV 300
QESKKEPGVV PRKSASFPPP PFYLNCDTRR NEKEGTLGKT QFSFPPLKIQ DSSDSGKKAY 360
TESLHGYTLS NSKGPVQPTA QGEEKGGLRI DMEDKMLPKC TDLKAKQLLL SDILNTKKLQ 420
WKSKEQKRKI QEDKNKQVKG LPSINTSLLT PPYLKFDTTE GQENVIRIAK VSLPQSRSKE 480
SSDAGRIACP EATHGELSSD VKQLKAHLLQ KEEKDREKVA DMTSVLDPNK MYLKAKKSPV 540
LHTHSFSDLQ WKTREQEEEK VQKVKSGPGV MLSKSPSRSS PLHLNVNTGF QEESIPILTR 600
PSFPLVKLQV SPDTEGGTCI RPIAGDILIY LQKGKHVSQN KEEDDVQIVS ILIFPKHQEE 660
KVQECEGEPG VVLTKSTSLP SLSQLELDKE THLGNEMLRL KRPILRRISH IGETVHRESV 720
VGDIPKDVKN EKQHIPQKEE RNQKKIIDMR GTDITLKSKK SPRSCMLHRT ELHVNIGGQG 780
RKEHEGQDKP PGMIQRKMCI LFSKPLPSNL KLERATHADE ERLGGKTSFV LPLMPSALPD 840
TEKTADAEAR SGDVRKGKPH RSQKENRHEV KTIDMRFRIH CQEARISPMS HILNAKELVL 900
NINKLEKKVH KDKDEACVVL SRTFLSIPSA PPLYLDSGNK TDKDTPGITG SSCPQRTLHV 960
PSNTQKITNR DSVEGVDKNV VKQAEQYVPR PEAEQQLTSN FMISVQQRNQ PSRVRSEEDL 1020
NQLVLNSRDE DIYFTGFGTI RSGKRPEWLF TGKKAQPVKY KTETLTAFLS YPTMDATKMG 1080
GLEEDTEIMD NLNHKISPKA SVSLIRKISK ELYVTLGTPA NSKGFSVSER YAHQQETSSK 1140
VSPELAGSCK FDKPKEDGQS NDRISKMFSP KVLAPQTKGS LKKISIVTNW NAPQNIEEQD 1200
IVMKKQVIRR CEHGHKTRTN TILSKFPLQS GKQKTPSETD VDKKTTAHLS LQMLPGIHMD 1260
MTEIDPAKGG RKQALLISEQ EEGVLEFLPK SLFPPWTFQF QSGDLEEKHQ TDANTNINLE 1320
QKKLEMDNDS TVNQKEGKLK IGTNRALHLQ EEKTEMHKAR TANLEKERGR MDTSSSAHPH 1380
LLSLKAEESQ MKTQVITHRE NSRLIMQKQK KELEASNAKQ SIQLQKLFQR NVLDSFYSYV 1440
PLSPKRKDQK GRLTIRDLKR ELSTKYLTMK IQNHPIPQML NITGRGTPSN RKKLEYDVKL 1500
KNIASWSKDV SGIFIRSLSI SIMRSPHTDP KTNLEREKRI CLPKFQEKSP NTSEMSKRDT 1560
LTIVKGEQNF TNTVPQDPQP FAVDKQQMQK LPNVKSEANL RSEMNKKYLK AQTKERIVPE 1620
HDVSRIIKKP DLRIIEQEEK ILKRILTPTE CPSMLEDPKL PKQRDQSEPV WDMTTQKVQQ 1680
QKAFPGTVPI PPQVKSSEVK IVADSTNAEH LLPICEATKA ISESQVKNMI QDKVSSDKLD 1740
NIQAYKPDDL KSPPFPEGPD TISTAIYPKT QHKSLLEQFT PKEKNKLTSH LESKALEIQL 1800
NLIPEMARKS LQMFNFYPKG TISKDNSWRF YSRHKTMNFM SLEGTDTIEP NSKHKHQKDS 1860
PLASNMKTLI VDVSSDSEET ITKLQSINKL ENGTSAVTSA SEMLLPHTLQ NHSVKEKGKL 1920
LMHFSVKTLE IQMKAFPRIV RESYAMTSAH ERKKPLSNCI HPGFTGPKRQ NRILLLSEEK 1980
SLHQIDLDLQ YKYLRFLLGL PVGSTFPKPN VLPKHSKLNT IAVCKNVNAG GQSGSLSIDT 2040
ELLEQHISFK KQSPHENSSL IRKFPQPTLV CASDRDLHSP RKKDTQVLSE SEFHVTPEKN 2100
KQYHVWFQER NTCESVDLRT QRNATGSAVS CETQISEDFV DIQTDIESPA DLDECSCLEV 2160
SESEECVFLE ANSYLSQESE NILFELQTGI PLENVYKITT DLKSFYSEDS GSHCTRECRK 2220
ETLIITPPSC KSHKSRKYRS SSKMKSPDWL CHSSSNTAEI QSRSSSVSFS EEKISWTTKS 2280
RTSYSSAPLT ESNIKSHLAK NQGKSHRHPE SQERKKARSD LFRKNSSHWD HDYSCTHSKG 2340
KRDRKKRVYD YESERLDCFQ SKHKSASKPH HDDINFYSER KQNRPFFFAC VPADSLEVIP 2400
KTIRWTIPPE TLRKRNFRIP LVAKISSSWN IWSSSKKLLG SLSGSLTTVF HS 2452 
Gene Ontology
  
Interpro
  
Pfam
  
SMART
  
PROSITE
  
PRINTS