CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-010556
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 60S ribosomal protein L19 
Protein Synonyms/Alias
  
Gene Name
 Rpl19 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
21VLRCGKKKVWLDPNEubiquitination[1]
46QQIRKLIKDGLIIRKubiquitination[1]
80GRHMGIGKRKGTANAacetylation[2]
128HSLYLKVKGNVFKNKubiquitination[1]
153KADKARKKLLADQAEubiquitination[1]
180REERLQAKKEEIIKTacetylation[2]
180REERLQAKKEEIIKTubiquitination[1]
181EERLQAKKEEIIKTLubiquitination[1]
186AKKEEIIKTLSKEEEubiquitination[1]
190EIIKTLSKEEETKK*acetylation[2]
190EIIKTLSKEEETKK*ubiquitination[1]
195LSKEEETKK******acetylation[2]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023]
 [2] Calorie restriction and SIRT3 trigger global reprogramming of the mitochondrial protein acetylome.
 Hebert AS, Dittenhafer-Reed KE, Yu W, Bailey DJ, Selen ES, Boersma MD, Carson JJ, Tonelli M, Balloon AJ, Higbee AJ, Westphall MS, Pagliarini DJ, Prolla TA, Assadi-Porter F, Roy S, Denu JM, Coon JJ.
 Mol Cell. 2013 Jan 10;49(1):186-99. [PMID: 23201123
Functional Description
  
Sequence Annotation
 MOD_RES 13 13 Phosphoserine (By similarity).
 MOD_RES 187 187 Phosphothreonine (By similarity).  
Keyword
 3D-structure; Complete proteome; Direct protein sequencing; Phosphoprotein; Reference proteome; Ribonucleoprotein; Ribosomal protein. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 196 AA 
Protein Sequence
MSMLRLQKRL ASSVLRCGKK KVWLDPNETN EIANANSRQQ IRKLIKDGLI IRKPVTVHSR 60
ARCRKNTLAR RKGRHMGIGK RKGTANARMP EKVTWMRRMR ILRRLLRRYR ESKKIDRHMY 120
HSLYLKVKGN VFKNKRILME HIHKLKADKA RKKLLADQAE ARRSKTKEAR KRREERLQAK 180
KEEIIKTLSK EEETKK 196 
Gene Ontology
 GO:0022625; C:cytosolic large ribosomal subunit; IDA:MGI.
 GO:0003735; F:structural constituent of ribosome; IDA:MGI.
 GO:0006412; P:translation; IC:MGI. 
Interpro
 IPR027547; Ribosomal_L19/L19e.
 IPR023638; Ribosomal_L19/L19e_CS.
 IPR000196; Ribosomal_L19/L19e_dom.
 IPR015972; Ribosomal_L19/L19e_dom1.
 IPR015974; Ribosomal_L19/L19e_dom3. 
Pfam
 PF01280; Ribosomal_L19e 
SMART
  
PROSITE
 PS00526; RIBOSOMAL_L19E 
PRINTS