| Tag | Content |
|---|
| CPLM ID | CPLM-012818 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Polycystic kidney disease protein 1-like 3 |
Protein Synonyms/Alias | PC1-like 3 protein; Polycystin-1L3 |
Gene Name | Pkd1l3 |
Gene Synonyms/Alias | 71B10 |
Created Date | July 27, 2013 |
Organism | Mus musculus (Mouse) |
NCBI Taxa ID | 10090 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 69 | LAHTWNPKLRGFLKS | acetylation | [1] |
|
Reference | [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns. Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV. Cell Rep. 2012 Aug 30;2(2):419-31. [ PMID: 22902405] |
Functional Description | May function as an ion-channel regulator (By similarity). May function with PKD2L1 as heteromeric taste channels. |
Sequence Annotation | DOMAIN 34 142 C-type lectin.
DOMAIN 1018 1067 GPS.
DOMAIN 1129 1246 PLAT.
REGION 2053 2091 Channel pore-region.
MOTIF 1744 1754 Polycystin motif.
MOTIF 1840 1850 Polycystin motif.
CARBOHYD 89 89 N-linked (GlcNAc...) (Potential).
CARBOHYD 566 566 N-linked (GlcNAc...) (Potential).
CARBOHYD 579 579 N-linked (GlcNAc...) (Potential).
CARBOHYD 592 592 N-linked (GlcNAc...) (Potential).
CARBOHYD 923 923 N-linked (GlcNAc...) (Potential).
CARBOHYD 961 961 N-linked (GlcNAc...) (Potential).
DISULFID 55 141 By similarity.
DISULFID 116 133 By similarity. |
Keyword | Alternative splicing; Complete proteome; Disulfide bond; Glycoprotein; Ion channel; Ion transport; Lectin; Membrane; Reference proteome; Signal; Transmembrane; Transmembrane helix; Transport. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 2201 AA |
Protein Sequence | MLLQRRSWLW LYIRIGVILG DILGRKPSIR EQHGGNSCYQ LNRLFCDFQE ADNYCHAQRG 60
RLAHTWNPKL RGFLKSFLNE ETVWWVRGNL TLPGSHPGIN QTGGDDVLRN QKPGECPSVV 120
THSNAVFSRW NLCIEKHHFI CQAAAFPPQG ASIWRNEFGP GPLLPMKRRG AETERHMIPG 180
NGPPLAMCHQ PAPPELFETL CFPIDPASSA PPKATHRMTI TSLTGRPQVT SDTLASSSPP 240
QGTSDTPASS SPPQVTSATS ASSSPPQGTS DTPASSSPPQ VTSATSASSS PPQGTSDTPA 300
SSSPPQVTSA TSASSSPPQG TSDTPASSSP PQVTSATSAS SSPPQGTSDT PASSSPPQGT 360
LDTPSSSSPP QGTSDTPASS SPPQGTSETP ASNSPPQGTS ETPGFSSPPQ VTTATLVSSS 420
PPQVTSETPA SSSPTQVTSE TPASSSPTQV TSDTPASNSP PQGTSDTPGF SSPTQVTTAT 480
LVSSSPPQVT SDTPASSSPP QVTSDTPASS SPPQVTSETP ASSSPPQVTS DTSASISPPQ 540
VISDTPASSS PPQVTSETPA SSSPTNMTSD TPASSSPTNM TSDTPASSSP TNMTSDTPAS 600
SSPPWPVITE VTRPESTIPA GRSLANITSK AQEDSPLGVI STHPQMSFQS STSQALDETA 660
GERVPTIPDF QAHSEFQKAC AILQRLRDFL PTSPTSAQKN NSWSSQTPAV SCPFQPLGRL 720
TTTEKSSHQM AQQDMEQHPM DGAHNAFGIS AGGSEIQSDI QLRSEFEVED MLETSLMALG 780
EIHRAFCQQS LCPQSAVTLA SPSATLMLSS QNVSTLPLST YTLGEPAPLT LGFPSAEALK 840
ELLNKHPGVN LQVTGLAFNP FKTLDDKNIV GSIGNVQLSS AYQSIRVHDL IEDIEIMLWR 900
NASMETQPTS LNTSTDHFTI SVNITSLEKT LIVTIEPESP LLMTLHLGFQ DQLAHTHFYL 960
NISLPRDQVW QKDEEYTWVL TPENLWYGTG TYYIMAVENK STEAAQHTPV LVSVVTAVTQ 1020
CYFWDRYNRT WKSDGCQVGP KSTILKTQCL CDHLTFFSSD FFIVPRTVDV ENTIKLLLHV 1080
TNNPVGVSLL SSLLGFYILL AMWASRKDRE DMQKVKVTVL ADNDPSSASH YLIQVYTGYR 1140
RRAATTAKVV ITLYGSEGHS EPHHLCDPEK TVFERGALDV FLLSTGSWLG DLHGLRLWHD 1200
NSGDSPSWYV SQVIVSDMTT RKKWHFQCNC WLAVDLGNCE RDRVFTPASR SELSSFRHLF 1260
SSTIVEKFTQ DYLWLSVATR HPWNQFTRVQ RLSCCMALLL CDMVINIMFW KMGGTTAKRG 1320
TEQLGPLAVT LSELLVSIQT SIILFPIHLI FGRLFQLIHP PEALPQLPFI QAAWPPALVC 1380
ESPSLTQVVK ELKETVGFLL RRNTQLLSEC EPSSCSSCDI NKLAKLLSGL IYCHLEDEGC 1440
HQQTESHWED AVSENHYHFC RYLLQLLRRL KAHLEALGAT QDHQSCDFSE AVSQLQNLQE 1500
LLETQTLRRG PGPCRHSTSF PILSPGEGKK PMSFCLFRWL KCSCWLLLGV ISLASAFFIT 1560
LYSLELDKDQ ATSWVISMML SVLQDIFISQ PIKVIFLTLL FSLMANHMPW LNKDKEQHAR 1620
RIVALWAKCP WSAPGLRDKN NPIYTAPAMN NLAKPTRKAW KKQLSKLTGG TLVQILFLTL 1680
LMTTVYSAKD SSRFFLHRAI WKRFSHRFSE IKTVEDFYPW ANGTLLPNLY GDYRGFITDG 1740
NSFLLGNVLI RQTRIPNDIF FPGSLHKQMK SPPQHQEDRE NYGAGWVPPD TNITKVDSIW 1800
HYQNQESLGG YPIQGELATY SGGGYVVRLG RNHSAATRVL QHLEQRRWLD HCTKALFVEF 1860
TVFNANVNLL CAVTLILESS GVGTFLTSLQ LDSLTSLQSS ERGFAWIVSQ VVYYLLVCYY 1920
AFIQGCRLKR QRLAFFTRKR NLLDTSIVLI SFSILGLSMQ SLSLLHKKMQ QYHCDRDRFI 1980
SFYEALRVNS AVTHLRGFLL LFATVRVWDL LRHHAQLQVI NKTLSKAWDE VLGFILIIVV 2040
LLSSYAMTFN LLFGWSISDY QSFFRSIVTV VGLLMGTSKH KEVIALYPIL GSLLVLSSII 2100
LMGLVIINLF VSAILIAFGK ERKACEKEAT LTDMLLQKLS SLLGIRLHQN PSEEHADNTG 2160
SSNLRERSSK SMSSDAEVLA PADAVGSVSG TDGNSGSTKV L 2201 |
Gene Ontology | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. GO:0016020; C:membrane; IBA:RefGenome. GO:0005262; F:calcium channel activity; IBA:RefGenome. GO:0005509; F:calcium ion binding; IEA:InterPro. GO:0030246; F:carbohydrate binding; IEA:InterPro. GO:0071468; P:cellular response to acidity; IDA:BHF-UCL. GO:0001581; P:detection of chemical stimulus involved in sensory perception of sour taste; IDA:BHF-UCL. GO:0050982; P:detection of mechanical stimulus; IBA:RefGenome. GO:0007218; P:neuropeptide signaling pathway; IEA:InterPro. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |