CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-003205
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Protein tas 
Protein Synonyms/Alias
  
Gene Name
 tas 
Gene Synonyms/Alias
 ygdS; b2834; JW2802 
Created Date
 July 27, 2013 
Organism
 Escherichia coli (strain K12) 
NCBI Taxa ID
 83333 
Lysine Modification
Position
Peptide
Type
References
81AKHGSREKLIIASKVacetylation[1]
97GPSRNNDKGIRPDQAacetylation[1]
119EALHDSLKRLQTDYLacetylation[1]
195RYLHLADKHDLPRIVacetylation[1, 2]
Reference
 [1] Acetyl-Phosphate Is a Critical Determinant of Lysine Acetylation in E. coli.
 Weinert BT, Iesmantavicius V, Wagner SA, Schölz C, Gummesson B, Beli P, Nyström T, Choudhary C.
 Mol Cell. 2013 Jul 25;51(2):265-72. [PMID: 23830618]
 [2] Comprehensive profiling of protein lysine acetylation in Escherichia coli.
 Zhang K, Zheng S, Yang JS, Chen Y, Cheng Z.
 J Proteome Res. 2013 Feb 1;12(2):844-51. [PMID: 23294111] 
Functional Description
  
Sequence Annotation
 NP_BIND 234 244 NADP.
 ACT_SITE 53 53 Proton donor.  
Keyword
 3D-structure; Complete proteome; NADP; Oxidoreductase; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 346 AA 
Protein Sequence
MQYHRIPHSS LEVSTLGLGT MTFGEQNSEA DAHAQLDYAV AQGINLIDVA EMYPVPPRPE 60
TQGLTETYVG NWLAKHGSRE KLIIASKVSG PSRNNDKGIR PDQALDRKNI REALHDSLKR 120
LQTDYLDLYQ VHWPQRPTNC FGKLGYSWTD SAPAVSLLDT LDALAEYQRA GKIRYIGVSN 180
ETAFGVMRYL HLADKHDLPR IVTIQNPYSL LNRSFEVGLA EVSQYEGVEL LAYSCLGFGT 240
LTGKYLNGAK PAGARNTLFS RFTRYSGEQT QKAVAAYVDI ARRHGLDPAQ MALAFVRRQP 300
FVASTLLGAT TMDQLKTNIE SLHLELSEDV LAEIEAVHQV YTYPAP 346 
Gene Ontology
 GO:0004033; F:aldo-keto reductase (NADP) activity; TAS:EcoliWiki.
 GO:0034198; P:cellular response to amino acid starvation; IMP:EcoliWiki. 
Interpro
 IPR001395; Aldo/ket_red.
 IPR020471; Aldo/keto_reductase_subgr.
 IPR023210; NADP_OxRdtase_dom. 
Pfam
 PF00248; Aldo_ket_red 
SMART
  
PROSITE
  
PRINTS
 PR00069; ALDKETRDTASE.