CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-042347
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Transcriptional regulator ATRX 
Protein Synonyms/Alias
  
Gene Name
 ATRX 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
22NEASAVSKAMNSIRSubiquitination[1]
63ENLLGSIKEFRNRFIubiquitination[1, 2, 3, 4]
107LAGCVQRKDYTALTKubiquitination[1]
Reference
 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961]
 [2] A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles.
 Wagner SA, Beli P, Weinert BT, Nielsen ML, Cox J, Mann M, Choudhary C.
 Mol Cell Proteomics. 2011 Oct;10(10):M111.013284. [PMID: 21890473]
 [3] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983]
 [4] Integrated proteomic analysis of post-translational modifications by serial enrichment.
 Mertins P, Qiao JW, Patel J, Udeshi ND, Clauser KR, Mani DR, Burgess MW, Gillette MA, Jaffe JD, Carr SA.
 Nat Methods. 2013 Jul;10(7):634-7. [PMID: 23749302
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 160 AA 
Protein Sequence
XPDFVVCDEG HILKNEASAV SKAMNSIRSR RRIILTGTPL QNNLIEYHCM VNFIKENLLG 60
SIKEFRNRFI NPIQNGQCAD STMVDVRVMK KRAHILYEML AGCVQRKDYT ALTKFLPPKH 120
EYVLAVRMTS IQCKLYQYYL DHLTVLHLNK MGMLKSIKYF 160 
Gene Ontology
 GO:0005524; F:ATP binding; IEA:InterPro.
 GO:0003677; F:DNA binding; IEA:InterPro. 
Interpro
 IPR014001; Helicase_ATP-bd.
 IPR027417; P-loop_NTPase.
 IPR000330; SNF2_N. 
Pfam
 PF00176; SNF2_N 
SMART
  
PROSITE
 PS51192; HELICASE_ATP_BIND_1 
PRINTS