Tag | Content |
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CPLM ID | CPLM-002333 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Prothymosin alpha |
Protein Synonyms/Alias | Prothymosin alpha, N-terminally processed; Thymosin alpha |
Gene Name | Ptma |
Gene Synonyms/Alias | |
Created Date | July 27, 2013 |
Organism | Rattus norvegicus (Rat) |
NCBI Taxa ID | 10116 |
Lysine Modification | Position | Peptide | Type | References |
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15 | TSSEITTKDLKEKKE | acetylation | [1] |
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Reference | [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns. Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV. Cell Rep. 2012 Aug 30;2(2):419-31. [ PMID: 22902405] |
Functional Description | Prothymosin alpha may mediate immune function by conferring resistance to certain opportunistic infections. |
Sequence Annotation | MOD_RES 1 1 N-acetylmethionine (By similarity). MOD_RES 2 2 N-acetylserine; in Prothymosin alpha, N- MOD_RES 2 2 Phosphoserine (By similarity). MOD_RES 8 8 Phosphothreonine (By similarity). MOD_RES 9 9 Phosphoserine (By similarity). MOD_RES 10 10 Phosphoserine (By similarity). MOD_RES 13 13 Phosphothreonine (By similarity). MOD_RES 14 14 Phosphothreonine (By similarity). MOD_RES 15 15 N6-acetyllysine (By similarity). MOD_RES 102 102 Phosphothreonine (By similarity). MOD_RES 108 108 Phosphothreonine (By similarity). |
Keyword | Acetylation; Complete proteome; Direct protein sequencing; Nucleus; Phosphoprotein; Reference proteome. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 112 AA |
Protein Sequence | MSDAAVDTSS EITTKDLKEK KEVVEEAENG RDAPANGNAQ NEENGEQEAD NEVDEEEEEG 60 GEEEEEEEEG DGEEEDGDED EEAEAPTGKR VAEDDEDDDV ETKKQKKTDE DD 112 |
Gene Ontology | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. GO:0030154; P:cell differentiation; TAS:RGD. GO:0008283; P:cell proliferation; TAS:RGD. GO:0043066; P:negative regulation of apoptotic process; IDA:RGD. GO:0043154; P:negative regulation of cysteine-type endopeptidase activity involved in apoptotic process; IDA:RGD. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |