CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-015256
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 V-type proton ATPase subunit E 1 
Protein Synonyms/Alias
 V-ATPase subunit E 1; Vacuolar proton pump subunit E 1 
Gene Name
 Atp6v1e1 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Rattus norvegicus (Rat) 
NCBI Taxa ID
 10116 
Lysine Modification
Position
Peptide
Type
References
138RMIVRCRKQDFPLVKubiquitination[1]
Reference
 [1] Synaptic protein ubiquitination in rat brain revealed by antibody-based ubiquitome analysis.
 Na CH, Jones DR, Yang Y, Wang X, Xu Y, Peng J.
 J Proteome Res. 2012 Sep 7;11(9):4722-32. [PMID: 22871113
Functional Description
 Subunit of the peripheral V1 complex of vacuolar ATPase essential for assembly or catalytic function. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. 
Sequence Annotation
 MOD_RES 2 2 N-acetylalanine (By similarity).
 MOD_RES 56 56 Phosphotyrosine (By similarity).  
Keyword
 Acetylation; Complete proteome; Direct protein sequencing; Hydrogen ion transport; Hydrolase; Ion transport; Phosphoprotein; Reference proteome; Transport. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 226 AA 
Protein Sequence
MALSDADVQK QIKHMMAFIE QEANEKAEEI DAKAEEEFNI EKGRLVQTQR LKIMEYYEKK 60
EKQIEQQKKI QMSNLMNQAR LKVLRARDDL ITDLLNEAKQ RLSKVVKDTT RYQVLLDGLV 120
LQGLYQLLEP RMIVRCRKQD FPLVKAAVQK AIPMYKIATK KDVDVQIDLE AYLPEDIAGG 180
VEIYNGDRKI KVSNTLESRL DLIAQQMMPE VRGALFGANA NRKFLD 226 
Gene Ontology
 GO:0016324; C:apical plasma membrane; ISS:UniProtKB.
 GO:0005829; C:cytosol; ISS:UniProtKB.
 GO:0005768; C:endosome; ISS:UniProtKB.
 GO:0033178; C:proton-transporting two-sector ATPase complex, catalytic domain; IEA:InterPro.
 GO:0046961; F:proton-transporting ATPase activity, rotational mechanism; IEA:InterPro.
 GO:0015991; P:ATP hydrolysis coupled proton transport; IEA:InterPro. 
Interpro
 IPR002842; ATPase_V1/A1-cplx_esu. 
Pfam
 PF01991; vATP-synt_E 
SMART
  
PROSITE
  
PRINTS