| Tag | Content |
|---|
| CPLM ID | CPLM-008017 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | GTPase-activating protein GYP7 |
Protein Synonyms/Alias | GAP for YPT7 |
Gene Name | GYP7 |
Gene Synonyms/Alias | YDL234C |
Created Date | July 27, 2013 |
Organism | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) |
NCBI Taxa ID | 559292 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 285 | QKLLNNEKVKQIEQD | ubiquitination | [1] | | 287 | LLNNEKVKQIEQDYD | ubiquitination | [1] |
|
Reference | [1] Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation. Swaney DL, Beltrao P, Starita L, Guo A, Rush J, Fields S, Krogan NJ, Villén J. Nat Methods. 2013 Jul;10(7):676-82. [ PMID: 23749301] |
Functional Description | Most effectively accelerates the intrinsic GTPase activity of YPT7. It is also active, but to a lesser extent, on YPT31, YPT32, YPT1, YPT6 and SEC4. |
Sequence Annotation | DOMAIN 385 633 Rab-GAP TBC.
MOD_RES 265 265 Phosphoserine.
MOD_RES 339 339 Phosphoserine. |
Keyword | Complete proteome; GTPase activation; Phosphoprotein; Reference proteome. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 746 AA |
Protein Sequence | MSKILFCKSK VFLHPTSDAR DNIAGFLLLT LEANKLSHQA ILQYIPESGL STLEISKLLK 60
HEAKVGTCPT STPFVIENSI NFSNLVNTSL GQAFEISLSQ IYCIQFRPPS PNGWYVGSLV 120
IYPLTEQFTG FQPPVLFFHD QLCPSTTDKL KRLRKSMNPF DDSDELYWGG VDLRNKINEL 180
MELKKSNLEP EFWLVNPSLN DLRNFVSKDL LESYNNSKKD TTELATAGVK LNEKFQEWKW 240
NVMSKIADVT TKSTNFIDSW LTNNSPIQKS QIDNEYLQKL LNNEKVKQIE QDYDSARVYL 300
ANWSLGVKQE AERYQKQNKL FDSYRNNIFN DLNLTDELSD TEINNALQRQ FPLTEAKWNS 360
LWDENDGRLR VTVNEVKDFI FHGGLENDSL RGKVWGFLLE IYPWDSSQDE RVQIDQTLAA 420
EYDQLKLTWS KDFLQFDDED EEEYWNDQLF RISKDVRRCD RNLEIFQYNT IDGLPPPPQQ 480
LPANENNSTS PESANDESDD ADDGVRNPHL IHLQNILITY NVYNTNLGYV QGMTDLLSPI 540
YVIMKEEWKT FWCFTHFMDI MERNFLRDQS GIHEQMLTLV ELVQLMLPEL SEHLNKCDSG 600
NLFFCFRMLL VWFKREFEME DIMHIWENFW TFYYSSQFQL FFMLAILQKN SQAILQHLNQ 660
FDQILKFFNE LNGKLDWNDL MVRAELLFKK FEKMMHVMER DLQNVSSSSS SSSTGVLPCQ 720
SERLTLLLSK KPIIRHEGQR SKNSVK 746 |
Gene Ontology | GO:0005737; C:cytoplasm; IDA:SGD. GO:0005097; F:Rab GTPase activator activity; IDA:SGD. GO:0032889; P:regulation of vacuole fusion, non-autophagic; IMP:SGD. GO:0016192; P:vesicle-mediated transport; IDA:SGD. |
Interpro | |
Pfam | |
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