CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-043946
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 THUMP domain-containing protein 3 
Protein Synonyms/Alias
  
Gene Name
 THUMPD3 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
182VTDLPFGKRMGSKKRubiquitination[1, 2]
220VLLTQDTKCFTKALSubiquitination[1]
235GMRHVWRKVDTVWVNubiquitination[1]
Reference
 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961]
 [2] Integrated proteomic analysis of post-translational modifications by serial enrichment.
 Mertins P, Qiao JW, Patel J, Udeshi ND, Clauser KR, Mani DR, Burgess MW, Gillette MA, Jaffe JD, Carr SA.
 Nat Methods. 2013 Jul;10(7):634-7. [PMID: 23749302
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 269 AA 
Protein Sequence
XRNVKKEFTS HALDSHILDY YENPAIKEDV STLIGDDLAS CKDETDESSK EETEPQVLKF 60
RVTCNRAGEK HCFTSNEAAR DFGGAVQDYF KWKADMTNFD VEVLLNIHDN EVIVGIALTE 120
ESLHRRNITH FGPTTLRSTL AYGMLSKPSW GLPIDAVQWD ICNLPLRTGS VDIIVTDLPF 180
GKRMGSKKRN WNLYPACLRE MSRVCTPTTG RAVLLTQDTK CFTKALSGMR HVWRKVDTVW 240
VNVGGLRAAV YVLIRTPQAF VHPSEQDGE 269 
Gene Ontology
 GO:0003723; F:RNA binding; IEA:InterPro. 
Interpro
 IPR000241; RNA_methylase_dom.
 IPR004114; THUMP. 
Pfam
 PF02926; THUMP
 PF01170; UPF0020 
SMART
 SM00981; THUMP 
PROSITE
 PS51165; THUMP 
PRINTS