CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-026490
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Protein Rtcd1 
Protein Synonyms/Alias
 RNA terminal phosphate cyclase domain 1; RNA terminal phosphate cyclase domain 1, isoform CRA_a 
Gene Name
 Rtcd1 
Gene Synonyms/Alias
 rCG_28704 
Created Date
 July 27, 2013 
Organism
 Rattus norvegicus (Rat) 
NCBI Taxa ID
 10116 
Lysine Modification
Position
Peptide
Type
References
163KTRGYYPKGGGEVIVacetylation[1]
205VAGVLPLKVAKDMAAacetylation[1]
Reference
 [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405] 
Functional Description
  
Sequence Annotation
 NP_BIND 294 298 ATP (By similarity).
 ACT_SITE 320 320 Tele-AMP-histidine intermediate (By
 BINDING 104 104 ATP (By similarity).  
Keyword
 ATP-binding; Complete proteome; Nucleotide-binding; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 366 AA 
Protein Sequence
MEGQRVEVDG GIMEGGGQIL RVSTALSCLL GLPLRVQKIR AGRSTPGLRP QHLSGLEMVR 60
DLCDGHLEGA EIGSTEITFT PEKIRGGVHT ADTKTAGSVC LLMQVSMPCV LFAASPSELR 120
LKGGTNAEMA PQIDYTMMVF KPIAEKFGFT FNCDIKTRGY YPKGGGEVIV RMSPVKRLDP 180
INLTDRGSVT KIYGRAFVAG VLPLKVAKDM AAAAVRCLRK EIRDLYVSIQ PVQEARDQAF 240
GNGSGIIIVA ETSTGCLFAG SSLGKRGVNA DKVGIEAAEM LLANLRHGGT VDEYLQDQLI 300
IFMALASGIS RIKTGPVTLH TQTAIHFAEQ LAKAKFTVKK SEEEEDASKD TYIIECEGVG 360
MANPHL 366 
Gene Ontology
 GO:0005634; C:nucleus; IEA:Compara.
 GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
 GO:0003963; F:RNA-3'-phosphate cyclase activity; IEA:InterPro.
 GO:0006396; P:RNA processing; IEA:InterPro. 
Interpro
 IPR013791; RNA3'-term_phos_cycl_insert.
 IPR023797; RNA3'_phos_cyclase_dom.
 IPR000228; RNA3'_term_phos_cyc.
 IPR017770; RNA3'_term_phos_cyc_type_1.
 IPR020719; RNA3'_term_phos_cycl-like_CS.
 IPR013792; RNA3'P_cycl/enolpyr_Trfase_a/b. 
Pfam
 PF01137; RTC
 PF05189; RTC_insert 
SMART
  
PROSITE
 PS01287; RTC 
PRINTS