CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-030880
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Tubulin polyglutamylase complex subunit 2 
Protein Synonyms/Alias
 cDNA FLJ52501 
Gene Name
 TPGS2 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
14SPGLGCSKPHLEKLTubiquitination[1]
19CSKPHLEKLTLGITRubiquitination[1, 2]
42TEVTIIEKPPAERHMubiquitination[1, 3]
56MISSWEQKNNCVMPEubiquitination[1]
129CLVYKSGKPALAEDTubiquitination[3, 4]
Reference
 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961]
 [2] Integrated proteomic analysis of post-translational modifications by serial enrichment.
 Mertins P, Qiao JW, Patel J, Udeshi ND, Clauser KR, Mani DR, Burgess MW, Gillette MA, Jaffe JD, Carr SA.
 Nat Methods. 2013 Jul;10(7):634-7. [PMID: 23749302]
 [3] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983]
 [4] Global identification of modular cullin-RING ligase substrates.
 Emanuele MJ, Elia AE, Xu Q, Thoma CR, Izhar L, Leng Y, Guo A, Chen YN, Rush J, Hsu PW, Yen HC, Elledge SJ.
 Cell. 2011 Oct 14;147(2):459-74. [PMID: 21963094
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 265 AA 
Protein Sequence
MEEEASSPGL GCSKPHLEKL TLGITRILES SPGVTEVTII EKPPAERHMI SSWEQKNNCV 60
MPEDVKNFYL MTNGFHMTWS VKLDDLEDDT HEASDDQPEK PHFDSRSVIF ELDSCNGSGK 120
VCLVYKSGKP ALAEDTEIWF LDRALYWHFL TDTFTAYYRL LITHLGLPQW QYAFTSYGIS 180
PQAKQWFSMY KPITYNTNLL TEETDSFVNK LDPSKVFKSK NKIVIPKKKG PVQPAGGQKG 240
PSGPSGPSTS STSKSSSGSG NPTRK 265 
Gene Ontology
  
Interpro
 IPR018958; Cell_wall_assmbl_KNR4-like. 
Pfam
  
SMART
 SM00860; SMI1_KNR4 
PROSITE
  
PRINTS