| Tag | Content |
|---|
| CPLM ID | CPLM-012828 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Testin |
Protein Synonyms/Alias | |
Gene Name | Tes |
Gene Synonyms/Alias | |
Created Date | July 27, 2013 |
Organism | Rattus norvegicus (Rat) |
NCBI Taxa ID | 10116 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 102 | TNPVAAKKNVSINTV | acetylation | [1] | | 173 | ELSPKEVKEMEQFVK | acetylation | [1] |
|
Reference | [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns. Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV. Cell Rep. 2012 Aug 30;2(2):419-31. [ PMID: 22902405] |
Functional Description | Scaffold protein that may play a role in cell adhesion, cell spreading and in the reorganization of the actin cytoskeleton. Plays a role in the regulation of cell proliferation. May act as a tumor suppressor (By similarity). |
Sequence Annotation | DOMAIN 92 199 PET.
DOMAIN 232 295 LIM zinc-binding 1.
DOMAIN 297 357 LIM zinc-binding 2.
DOMAIN 360 419 LIM zinc-binding 3. |
Keyword | Cell junction; Complete proteome; Cytoplasm; LIM domain; Metal-binding; Reference proteome; Repeat; Zinc. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 419 AA |
Protein Sequence | MDLETKMKKM GLGHEQGFGA PCLKCKENCE GFELHFWRKI CRNCKCGQEE HDVLLSTEED 60
RKVGRLFEDT KYTTLIAKLK SDGIPMYKRN VMILTNPVAA KKNVSINTVT YEWAPPVQNQ 120
ALARQYMQML PKEKQPVAGS EGAQYRKKQL AKQLPAHDQD PSKCHELSPK EVKEMEQFVK 180
KYKSEALGVG DVKLPSEMNA QGDKVHNPAG DRNTPAAVGS KDKSAEAKKT QYSCYCCKNT 240
MREGDPAIYA ERAGYDKLWH PACFICSTCG ELLVDMIYFW KNGKLYCGRH YCDSEKPRCA 300
GCDELIFSNE YTQAENQNWH LKHFCCFDCD NILAGKIYVM VRDKPVCKPC YVKNHAVVCQ 360
GCHNAIDPEV QRVTYNNFSW HASTECFLCS CCSKCLIGQK FMPVEGMVFC SVECKKMMS 419 |
Gene Ontology | GO:0005737; C:cytoplasm; ISS:UniProtKB. GO:0005925; C:focal adhesion; IEA:UniProtKB-SubCell. GO:0008270; F:zinc ion binding; ISS:UniProtKB. GO:0008285; P:negative regulation of cell proliferation; ISS:UniProtKB. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |