CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-038028
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 A-kinase anchor protein 12 
Protein Synonyms/Alias
  
Gene Name
 Akap12 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Rattus norvegicus (Rat) 
NCBI Taxa ID
 10116 
Lysine Modification
Position
Peptide
Type
References
512LFSSSGLKKLSGKKQacetylation[1]
601ITPWASFKKMVTPKKacetylation[1]
1246WLDGEKVKEEQEVFVacetylation[1]
Reference
 [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 1595 AA 
Protein Sequence
MGAGSSTEQR SPEQPAGSDT PSELVLSGHG PAAEASGAAG DPADADPATK LPQKNGQLST 60
VNGVAEQGDV HVQEENQEGQ EEEVVDEDVG QRESEDVREK DRVEEMAANS TAVEDITKDG 120
QEETSEIIEQ IPASESNVEE MVQPAESQAN DVGFKKVFKF VGFKFTVKKD KNEKSDTVQL 180
LTVKKDEGEG AEASVGAGDH QEPSVETAVG ESASKESELK QSTEKQEGTL KQEQSSTEIP 240
LQAESDQAAE EEAKDEGEEK QEKEPTKSPE SPSSPVSSET TSSFKKFFTH GWAGWRKKTS 300
FKKSKEDDLE TAEKRKEQEA EKVDEEEKEK TEPASEEQEP AEDTDQARLS ADYEKVELPL 360
EDQVGDLEAS SEEKCAPLAT EVFDEKMEAH QEVVAEVHVS TVEKTEEEQG GGGEAEGGVV 420
VEGTGESLPP EKLAEPQEVP QEAEPAEELM KSREMCVSGG DHTQLTDLSP EEKTLPKHPE 480
GIVSEVEMLS SQERIKVQGS PLKKLFSSSG LKKLSGKKQK GKRGGGGDEE PGEYQHIHTE 540
SPESADEQKG ESSASSPEEP EETTCLEKGP LEAPQDGEAE EGTTSDGEKK REGITPWASF 600
KKMVTPKKRV RRPSESDKEE ELEKVKSATL SSTDSTVSEM QDEVKTVGEE QKPEEPKRRV 660
DTSVSWEALI CVGSSKKRAR KASSSDDEGG PRTLGGDSHR AEEASKDKEA GTDAVPASTQ 720
EQDQAQGSSS PEPAGSPSEG EGVSTWESFK RLVTPRKKSK SKLEEKAEDS SVEQLSTEIE 780
PSREESWVSI KKFIPGRRKK RADGKQEQAT VEDSGPVEIN EDDPDVPAVV PLSEYDAVER 840
EKMEAQGNAE LPQLLGAVYV SEELSKTLVH TVSVAVIDGT RAVTSVEERS PSWISASVTE 900
PLEHTAGEAM PPVEEVTEKD IIAEETPVLT QTLPEGKDAH DDMVTSEVDF TSEAVTATET 960
SEALRTEEVT EASGAEETTD MVSAVSQLTD SPDTTEEATP VQEVEGGVLD TEEEERQTQA 1020
ILQAVADKVK EESQVPATQT VQRTGSKALE KVEEVEEDSE VLASEKEKDV MPKGPVQEAG 1080
AEHLAQGSET GQATPESLEV PEVTADVDHV ATCQVIKLQQ LMEQAVAPES SETLTDSETN 1140
GSTPLADSDT ADGTQQDETI DSQDSKATAA VRQSQVTEEE AATAQKEEPS TLPNNVPAQE 1200
EHGEEPGRDV LEPTQQELAA AAVPVLAKTE VGQEGEVDWL DGEKVKEEQE VFVHSGPNSQ 1260
KAADVTYDSE VMGVAGCQEK ESTEVQSLSL EEGEMETDVE KEKRETKPEQ VSEEGEQETA 1320
APEHEGTYGK PVLTLDMPSS ERGKALGSLG GSPSLPDQDK AGCIEVQVQS LDTTVTQTAE 1380
AVEKVIETVV ISETGESPEC VGAHLLPAEK SSATGGHWTL QHAEDTVPLG PESQAESIPI 1440
IVTPAPESTL HPDLQGEISA SQRERSEEED KPDAGPDADG KESTAIEKVL KAEPEILELE 1500
SKSNKIVLNV IQTAVDQFAR TETAPETHAY DSQTQVPCRL TAREPNRCWT KMKVAKMKHP 1560
VPQPREDLQV LTVLEAWAQP RKCLPRLQLK APVSK 1595 
Gene Ontology
 GO:0006605; P:protein targeting; IEA:InterPro.
 GO:0007165; P:signal transduction; IEA:InterPro. 
Interpro
 IPR001573; Pkinase-A_anch_WSK-motif.
 IPR018459; RII_binding_1. 
Pfam
 PF10522; RII_binding_1
 PF03832; WSK 
SMART
  
PROSITE
  
PRINTS