CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-008500
UniProt Accession
Genbank Protein ID
 U31935 
Genbank Nucleotide ID
Protein Name
 Adenylyl cyclase-associated protein 2 
Protein Synonyms/Alias
 CAP 2 
Gene Name
 Cap2 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Rattus norvegicus (Rat) 
NCBI Taxa ID
 10116 
Lysine Modification
Position
Peptide
Type
References
276NQGEAITKGLRHVTDubiquitination[1]
Reference
 [1] Synaptic protein ubiquitination in rat brain revealed by antibody-based ubiquitome analysis.
 Na CH, Jones DR, Yang Y, Wang X, Xu Y, Peng J.
 J Proteome Res. 2012 Sep 7;11(9):4722-32. [PMID: 22871113
Functional Description
 May have a regulatory bifunctional role. 
Sequence Annotation
 DOMAIN 318 455 C-CAP/cofactor C-like.
 MOD_RES 262 262 Phosphoserine (By similarity).  
Keyword
 Cell membrane; Complete proteome; Membrane; Phosphoprotein; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 477 AA 
Protein Sequence
MADMLGLMQR LEFAVSRLER LSSGLHEPPG GCGEVNSLSR GIVAPSVEAF DKLINSMVAE 60
FLKNSRVLAG DVETHAEMVH GAFQAQRAFL LMVSQHQQPQ ENEVAVLLKP ISEKIQEIQT 120
FRERNRGSDM FNHLSAVSES IAALGWIAVS PKPGPYVKEM NDAATFYTNR VLRDYKHSDL 180
RHVDWVRSYL KIWSELQAYI KEHHTTGLTW SKTGPVASTA SAFSILSSGP GLPPPPPPPP 240
PPGPPPPFEN EGGKEEPSPS RSALFAQLNQ GEAITKGLRH VTDDKKIYKN PSLRAQGQIR 300
SPTKTRTPSP TSSKSNSPQK HAPVLELEGK KWRVEYQEDR NDLVISETEL KQVAYIFKCD 360
KSTLQIKGKV NSITVDNCKK FGLVFDHVVG IVEVINSKDI QIQVMGRVPT ISINKTEGCH 420
LYLSKDALDC EIVSAKSSEM NVLVPQGDDY REFPIPEQFK TIWDGSKLIT EPAEIMA 477 
Gene Ontology
 GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
 GO:0030036; P:actin cytoskeleton organization; TAS:RGD.
 GO:0000902; P:cell morphogenesis; IEA:InterPro. 
Interpro
 IPR001837; Adenylate_cyclase-assoc_CAP.
 IPR013912; Adenylate_cyclase-assoc_CAP_C.
 IPR013992; Adenylate_cyclase-assoc_CAP_N.
 IPR017901; C-CAP_CF_C-like.
 IPR016098; CAP/MinC_C.
 IPR018106; CAP_CS.
 IPR006599; CARP_motif. 
Pfam
 PF08603; CAP_C
 PF01213; CAP_N 
SMART
 SM00673; CARP 
PROSITE
 PS51329; C_CAP_COFACTOR_C
 PS01088; CAP_1
 PS01089; CAP_2 
PRINTS