| Tag | Content |
|---|
| CPLM ID | CPLM-022467 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Leucine-rich repeat transmembrane protein FLRT1 |
Protein Synonyms/Alias | Fibronectin-like domain-containing leucine-rich transmembrane protein 1 |
Gene Name | FLRT1 |
Gene Synonyms/Alias | UNQ752/PRO1483 |
Created Date | July 27, 2013 |
Organism | Homo sapiens (Human) |
NCBI Taxa ID | 9606 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 578 | DYMESGTKKDNSILE | acetylation | [1] | | 579 | YMESGTKKDNSILEI | acetylation | [1] |
|
Reference | [1] Regulation of cellular metabolism by protein lysine acetylation. Zhao S, Xu W, Jiang W, Yu W, Lin Y, Zhang T, Yao J, Zhou L, Zeng Y, Li H, Li Y, Shi J, An W, Hancock SM, He F, Qin L, Chin J, Yang P, Chen X, Lei Q, Xiong Y, Guan KL. Science. 2010 Feb 19;327(5968):1000-4. [ PMID: 20167786] |
Functional Description | May have a function in cell adhesion and/or receptor signaling. |
Sequence Annotation | DOMAIN 21 53 LRRNT.
REPEAT 54 75 LRR 1.
REPEAT 79 99 LRR 2.
REPEAT 100 121 LRR 3.
REPEAT 124 145 LRR 4.
REPEAT 150 171 LRR 5.
REPEAT 172 192 LRR 6.
REPEAT 195 218 LRR 7.
REPEAT 221 241 LRR 8.
REPEAT 243 264 LRR 9.
REPEAT 267 288 LRR 10.
DOMAIN 300 352 LRRCT.
DOMAIN 406 501 Fibronectin type-III.
CARBOHYD 221 221 N-linked (GlcNAc...) (Potential).
CARBOHYD 277 277 N-linked (GlcNAc...) (Potential). |
Keyword | Cell adhesion; Complete proteome; Glycoprotein; Leucine-rich repeat; Membrane; Reference proteome; Repeat; Signal; Transmembrane; Transmembrane helix. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 646 AA |
Protein Sequence | MDLRDWLFLC YGLIAFLTEV IDSTTCPSVC RCDNGFIYCN DRGLTSIPAD IPDDATTLYL 60
QNNQINNAGI PQDLKTKVNV QVIYLYENDL DEFPINLPRS LRELHLQDNN VRTIARDSLA 120
RIPLLEKLHL DDNSVSTVSI EEDAFADSKQ LKLLFLSRNH LSSIPSGLPH TLEELRLDDN 180
RISTIPLHAF KGLNSLRRLV LDGNLLANQR IADDTFSRLQ NLTELSLVRN SLAAPPLNLP 240
SAHLQKLYLQ DNAISHIPYN TLAKMRELER LDLSNNNLTT LPRGLFDDLG NLAQLLLRNN 300
PWFCGCNLMW LRDWVKARAA VVNVRGLMCQ GPEKVRGMAI KDITSEMDEC FETGPQGGVA 360
NAAAKTTASN HASATTPQGS LFTLKAKRPG LRLPDSNIDY PMATGDGAKT LAIHVKALTA 420
DSIRITWKAT LPASSFRLSW LRLGHSPAVG SITETLVQGD KTEYLLTALE PKSTYIICMV 480
TMETSNAYVA DETPVCAKAE TADSYGPTTT LNQEQNAGPM ASLPLAGIIG GAVALVFLFL 540
VLGAICWYVH QAGELLTRER AYNRGSRKKD DYMESGTKKD NSILEIRGPG LQMLPINPYR 600
AKEEYVVHTI FPSNGSSLCK ATHTIGYGTT RGYRDGGIPD IDYSYT 646 |
Gene Ontology | GO:0005887; C:integral to plasma membrane; NAS:UniProtKB. GO:0005578; C:proteinaceous extracellular matrix; NAS:UniProtKB. GO:0030674; F:protein binding, bridging; NAS:UniProtKB. GO:0005057; F:receptor signaling protein activity; NAS:UniProtKB. GO:0007155; P:cell adhesion; IEA:UniProtKB-KW. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |