CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-000814
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Putative acyltransferase Rv0859 
Protein Synonyms/Alias
  
Gene Name
 fadA 
Gene Synonyms/Alias
 Rv0859 
Created Date
 July 27, 2013 
Organism
 Mycobacterium tuberculosis 
NCBI Taxa ID
 1773 
Lysine Modification
Position
Peptide
Type
References
189WSGGYFAKSVVPVRDpupylation[1]
Reference
 [1] Prokaryotic ubiquitin-like protein (Pup) proteome of Mycobacterium tuberculosis [corrected] .
 Festa RA, McAllister F, Pearce MJ, Mintseris J, Burns KE, Gygi SP, Darwin KH.
 PLoS One. 2010 Jan 6;5(1):e8589. [PMID: 20066036
Functional Description
  
Sequence Annotation
 ACT_SITE 92 92 Acyl-thioester intermediate (By
 ACT_SITE 359 359 Proton acceptor (By similarity).
 ACT_SITE 389 389 Proton acceptor (By similarity).
 CROSSLNK 189 189 Isoglutamyl lysine isopeptide (Lys-Gln)  
Keyword
 3D-structure; Acyltransferase; Complete proteome; Isopeptide bond; Reference proteome; Transferase; Ubl conjugation. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 403 AA 
Protein Sequence
MSEEAFIYEA IRTPRGKQKN GSLHEVKPLS LVVGLIDELR KRHPDLDENL ISDVILGCVS 60
PVGDQGGDIA RAAVLASGMP VTSGGVQLNR FCASGLEAVN TAAQKVRSGW DDLVLAGGVE 120
SMSRVPMGSD GGAMGLDPAT NYDVMFVPQS IGADLIATIE GFSREDVDAY ALRSQQKAAE 180
AWSGGYFAKS VVPVRDQNGL LILDHDEHMR PDTTKEGLAK LKPAFEGLAA LGGFDDVALQ 240
KYHWVEKINH VHTGGNSSGI VDGAALVMIG SAAAGKLQGL TPRARIVATA TSGADPVIML 300
TGPTPATRKV LDRAGLTVDD IDLFELNEAF ASVVLKFQKD LNIPDEKLNV NGGAIAMGHP 360
LGATGAMILG TMVDELERRN ARRALITLCI GGGMGVATII ERV 403 
Gene Ontology
 GO:0005618; C:cell wall; IDA:MTBBASE.
 GO:0005886; C:plasma membrane; IDA:MTBBASE.
 GO:0016747; F:transferase activity, transferring acyl groups other than amino-acyl groups; IEA:InterPro. 
Interpro
 IPR002155; Thiolase.
 IPR016039; Thiolase-like.
 IPR016038; Thiolase-like_subgr.
 IPR020615; Thiolase_acyl_enz_int_AS.
 IPR020610; Thiolase_AS.
 IPR020617; Thiolase_C.
 IPR020613; Thiolase_CS.
 IPR020616; Thiolase_N. 
Pfam
 PF02803; Thiolase_C
 PF00108; Thiolase_N 
SMART
  
PROSITE
 PS00098; THIOLASE_1
 PS00737; THIOLASE_2
 PS00099; THIOLASE_3 
PRINTS