CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-014410
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Synaptonemal complex protein 1 
Protein Synonyms/Alias
 SCP-1 
Gene Name
 Sycp1 
Gene Synonyms/Alias
 Scp1 
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
509ELEKEKLKNTELTASubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023
Functional Description
 Major component of the transverse filaments of synaptonemal complexes (SCS), formed between homologous chromosomes during meiotic prophase. 
Sequence Annotation
 MOTIF 114 117 Nuclear localization signal (Potential).
 MOTIF 697 700 Nuclear localization signal (Potential).
 MOTIF 898 901 Nuclear localization signal (Potential).
 CROSSLNK 292 292 Glycyl lysine isopeptide (Lys-Gly)  
Keyword
 Cell cycle; Cell division; Chromosome; Coiled coil; Complete proteome; DNA-binding; Isopeptide bond; Meiosis; Nucleus; Reference proteome; Ubl conjugation. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 993 AA 
Protein Sequence
MEKQKPFTLF VPPRLSSSQV SAVKPQTAGG DSNYFKTANK CTEGDFGVPF TMSSRENIDK 60
DPAFQKLSIL PMLEQVANSG SCHYQEGVND SDFENSEPMS RLYSKLYKEA EKIKKWKVSI 120
ESELKQKENK LQENRKIIEA QRKAIQELQF ENEKVSLKLE EEIQENKDLI KENNATIHWC 180
NLLKETCARS AEKTNKYEYE REETRQVYVD LNSNIEKMIL AFEELRVQAE NARLEMHFKL 240
KEDHEKIQHL EEEYQKEVNN KENQVSELLI QSAEKENKMK DLTFLLEESR DKANQLEEKT 300
KLQDENLKEL SEKKDHLTSE LEDIKMSMQR SMSTQKALEE DLQIATKTIS QLTEVKEAQM 360
EELNKAKTTH SFVVTELKAT TCTLEELLRT EQQRLEKNED QLKLITVELQ KKSNELEEMT 420
KFKNNKEVEL EELKNILAED QKLLDEKKQV EKLAEELQEK EQELTFLLET REKEVHDLQE 480
QVTVTKTSEQ HYLKQVEEMK TELEKEKLKN TELTASCDML LLENKKFVQE ASDMALELKK 540
HQEDIINCKK QEERLLKQIE NLEEKEMHLR DELESVRKEF IQQGDEVKCK LDKSEENARS 600
IECEVLKKEK QMKILESKCN NLKKQVENKS KNIEELHQEN KTLKKKSSAE IKQLNAYEIK 660
VSKLELELES TKQRFEEMTN NYQKEIENKK ISEGKLLGEV EKAKATVDEA VKLQKEIDLR 720
CQHKIAEMVA LMEKHKHQYD KIVEERDSEL GLYKNREQEQ SSAKIALETE LSNIRNELVS 780
LKKQLEIEKE EKEKLKMAKE NTAILKDKKD KKIQASLLES PEATSWKFDS KTTPSQNISR 840
LSSSMDSGKS KDNRDNLRAS AKSILPTTVT KEYTVKTPTK KSIYQRENKY IPTGGSNKKR 900
KTAFEFDVNS DSSETADLLS LVSEEDVSNR LYDNNPPDSH LLVKTPKQTP LSLSTPASFM 960
KFGSLKKMRE DRWTTIAKID RKRRLKEAEK LFS 993 
Gene Ontology
 GO:0000801; C:central element; IDA:MGI.
 GO:0000800; C:lateral element; TAS:HGNC.
 GO:0001673; C:male germ cell nucleus; IDA:MGI.
 GO:0005654; C:nucleoplasm; TAS:Reactome.
 GO:0000802; C:transverse filament; IDA:MGI.
 GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
 GO:0051301; P:cell division; IEA:UniProtKB-KW.
 GO:0032880; P:regulation of protein localization; IMP:MGI.
 GO:0007130; P:synaptonemal complex assembly; IDA:HGNC. 
Interpro
 IPR008827; SCP-1. 
Pfam
 PF05483; SCP-1 
SMART
  
PROSITE
  
PRINTS