CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-038884
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Protein Abca1 
Protein Synonyms/Alias
  
Gene Name
 Abca1 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Rattus norvegicus (Rat) 
NCBI Taxa ID
 10116 
Lysine Modification
Position
Peptide
Type
References
260EGGGLKIKSLNWYEDubiquitination[1]
1963VPEKEVGKVGEWAIRubiquitination[1]
Reference
 [1] Synaptic protein ubiquitination in rat brain revealed by antibody-based ubiquitome analysis.
 Na CH, Jones DR, Yang Y, Wang X, Xu Y, Peng J.
 J Proteome Res. 2012 Sep 7;11(9):4722-32. [PMID: 22871113] 
Functional Description
  
Sequence Annotation
  
Keyword
 ATP-binding; Complete proteome; Nucleotide-binding; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 2201 AA 
Protein Sequence
MPSAGTLPWV QGIICNANNP CFRYPTPGEA PGVVGNFNKS IVSRLFSDAQ RILLYSQKDT 60
SIRDMHKVLR TLQQIKHPNS NLKLQDFLVD NETFSGFLQH SLSLPRSAVD NLLQADVSLQ 120
KVFLQGYQLH LASLCNGSKL EEIIRLGDLE VSALCSLPRE KLDAAERELR SNMDILKPVM 180
TKLNSTSLLP TQHLAEATTT LLDSLGGLAQ ELFSTKSWSD MRQEVMFLTN VNNSGSSTQI 240
YQAVSRIVCG HPEGGGLKIK SLNWYEDNNY KALFGGNGTE EDTDTFYDNS TTPYCNDLMK 300
NLESSPLSRI IWKALKPLLI GKILYTPDTP ATRQVMAEVN KTFQELALFH DLEGMWEELS 360
PQIWTFMESS QEMDLVRTML DSRGNDQFWE RKLDGLDWTA QDIMAFLAKN PEDVQSPNGS 420
VYTWREAFNE TNQAIQTISR FMECVNLNKL EPIPTEVRLI NKSMELLDER KFWAGIVFTG 480
ITPDSVELPH HVKYKIRMDI DNVERTNKIK DGYWDPGPRA DPFEDMRYVW GGFAYLQDVV 540
EQAIIRVLTG TEKKTGVYVQ QMPYPCYVDD IFLRVMSRSM PLFMTLAWIY SVAVIIKSIV 600
YEKEARLKET MRIMGLDNGI LWFSWFISSL IPLLVSAGLL VIILKLGDLL PYSDPSVVFV 660
FLSVFAVVTI LQCFLISTLF SRTNLAAACG GIIYFTLYLP YVLCVAWQDY VGFSIKIFAS 720
LLSPVAFGFG CEYFALFEEQ GIGVQWDNLF KSPVEEDGFN LTTSVSMMLF DTFIYGVMTW 780
YIEAVFPGQY GIPRPWYFPC TKSYWFGEEI DEKSHPGSSQ KGASEICMEE EPTHLKLGVS 840
IQNLVKVYRD GMKVAVDGLA LNFYEGQITS FLGHNGAGKT TTMSILTGLF PPTSGTAYIL 900
GKDIRSEMNS IRQNLGVCPQ HNVLFDMLTV EEHIWFYARL KGLSEKHVKA EMEQMALDVG 960
LPPSKLKSKT SQLSGGMQRK LSVALAFVGG SKVVILDEPT AGVDPYSRRG IWELLLKYRQ 1020
GRTIILSTHH MDEADILGDR IAIISHGKLC CVGSSLFLKN QLGTGYYLTL VKKDVESSLS 1080
SCRNSSSTVS CLKKEDSVSQ SSSDAGLGSD HESDTLTIDV SAISNLIRKH VSEARLVEDI 1140
GHELTYVLPY EAAKEGAFVE LFHEIDDRLS DLGISSYGIS ETTLEEIFLK VAEESGVDAE 1200
TSDGTLPARR NRRAFGDKQS CLHPFTEDDA VDPNDSDLDP ESRETDLLSG MDGKGSYQLK 1260
GWKLTQQQFV ALLWKRLLIA RRSRKGFFAQ IVLPAVFVCI ALVFSLIVPP FGKYPNLELQ 1320
PWMYNEQYTF VSNDAPEDMG TQELLNALTK DPGFGTRCME GNPIPNTPCL VGEEDWTTGP 1380
VPQTLMDLFQ NGNWTMKNPS PSCQCSSDKI KKMLPVCPPG AGGLPPPQRK QKTADILQNL 1440
TGRNISDYLV KTYVQIIAKS LKNKVWVNEF RYGGFSLGVS DSQALPPSQE VNNAIKQMKK 1500
LLKLTKDSSA DRFLSSLGRF MTGLDTKNNV KVWFNNKGWH AISSFLNVIN NAILRANLQK 1560
GENPSQYGIT AFNHPLNLTK QQVGKTAKMT TSVDVLVSIC VIFAMSFVPA SFVVFLIQER 1620
VSKAKHLQFI CGVKPVIYWL SNFVWDMCNY VVPATLVVII FICFQQKSYV SSTNLPVLAL 1680
LLLLYGWSIT PLMYPASFVF KIPSTAYVVL TSVNLFIGIN GSVATFVLEL FTNNKFNDIN 1740
DILKSVFLIF PHFCLGRGLI DMVKNQAMAD ALERFGENRF VSPLSWDLVG RNENAMAVEG 1800
VVFFLVTVLI QYRFFIRPRP VKARLPPLND EDEDVRRERQ RILEGGGQND ILEIKELTKI 1860
YRRKRKPAVD RICVGIPPGE CFGLLGVNGA GKTSTFKMLT GDTAVTRGDA LLNKNSILSN 1920
IHEVHQNMGY CPQFDAITEL LTGREHLEFF ALLRGVPEKE VGKVGEWAIR KLGLVKYGEK 1980
YASNYSGGNK RKLSTAIALI GGPPVVFLDE PTTGMDPKAR RFLWNCALSI IKEGRSVVLT 2040
SHSMEECEAL CTRMAIMVNG RFRCLGSVQH LKNRFGDGYT IVVRIAGSNP DLKPVQEFFG 2100
LAFPGSVLKE KHRNMLQYQL PSSLSSLARI FSILSQSKKR LHIEDYSVSQ TTLDQVFVNF 2160
AKDQSDDDHL KDLSLHKNQT VVDVAVLTSF LQDEKVKESY V 2201 
Gene Ontology
 GO:0009986; C:cell surface; IDA:RGD.
 GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
 GO:0042626; F:ATPase activity, coupled to transmembrane movement of substances; IDA:RGD.
 GO:0071397; P:cellular response to cholesterol; IEP:RGD.
 GO:0030301; P:cholesterol transport; IDA:RGD.
 GO:0042158; P:lipoprotein biosynthetic process; IMP:RGD.
 GO:0015914; P:phospholipid transport; IDA:RGD.
 GO:0042493; P:response to drug; IEP:RGD.
 GO:0007584; P:response to nutrient; IEP:RGD. 
Interpro
 IPR003593; AAA+_ATPase.
 IPR026082; ABC_A.
 IPR003439; ABC_transporter-like.
 IPR017871; ABC_transporter_CS.
 IPR027417; P-loop_NTPase. 
Pfam
 PF00005; ABC_tran 
SMART
 SM00382; AAA 
PROSITE
 PS00211; ABC_TRANSPORTER_1
 PS50893; ABC_TRANSPORTER_2 
PRINTS