CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-039884
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Ryanodine receptor 2 
Protein Synonyms/Alias
  
Gene Name
 RYR2 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
238DGDTPDMKCDDMLTCubiquitination[1]
Reference
 [1] Landscape of the PARKIN-dependent ubiquitylome in response to mitochondrial depolarization.
 Sarraf SA, Raman M, Guarani-Pereira V, Sowa ME, Huttlin EL, Gygi SP, Harper JW.
 Nature. 2013 Apr 18;496(7445):372-6. [PMID: 23503661] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Ion channel; Ion transport; Membrane; Reference proteome; Transmembrane; Transport. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 328 AA 
Protein Sequence
MEPTLRILAI LHTVISFFCI IGYYCLKVPL VIFKREKEVA RKLEFDGLYI TEQPSEDDIK 60
GQWDRLVINT QSFPNNYWDK FVKRKVMDKY GEFYGRDRIS ELLGMDKAAL DFSDAREKKK 120
PKKDSSLSAV LNSIDVKYQM WKLGVVFTDN SFLYLAWYMT MSVLGHYNNF FFAAHLLDIA 180
MGFKTLRTIL SSVTHNGKQL VLTVGLLAVV VYLYTVVAFN FFRKFYNKSE DGDTPDMKCD 240
DMLTCYMFHM YVGVRAGGGI GDEIEDPAGD EYEIYRIIFD ITFFFFVIVI LLAIIQGLII 300
DAFGELRDQQ EQVKEDMEVF SDVSYKQR 328 
Gene Ontology
 GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
 GO:0005219; F:ryanodine-sensitive calcium-release channel activity; IEA:InterPro.
 GO:0006874; P:cellular calcium ion homeostasis; IEA:InterPro. 
Interpro
 IPR005821; Ion_trans_dom.
 IPR009460; Ryanrecept_TM4-6. 
Pfam
 PF00520; Ion_trans
 PF06459; RR_TM4-6 
SMART
  
PROSITE
  
PRINTS