UniProt Accession

 D6RFX5_HUMAN; D6RFX5 

Genbank Protein ID

 AC021180 

Genbank Nucleotide ID

  

Protein Name

 Amphiregulin 

Protein Synonyms/Alias

  

Gene Name

 AREG 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Homo sapiens (Human) 

NCBI Taxa ID

 9606 

Lysine Modification

Position	Peptide	Type	References
109	VRVEQVVKPPQNKTE	ubiquitination	[1]
187	RCGEKSMKTHSMIDS	ubiquitination	[2]

Reference

 [1] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983]
 [2] Landscape of the PARKIN-dependent ubiquitylome in response to mitochondrial depolarization.
 Sarraf SA, Raman M, Guarani-Pereira V, Sowa ME, Huttlin EL, Gygi SP, Harper JW.
 Nature. 2013 Apr 18;496(7445):372-6. [PMID: 23503661] 

Functional Description

  

Sequence Annotation

  

Keyword

 Complete proteome; Reference proteome. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 274 AA 

Protein Sequence

Gene Ontology

  

Interpro

 IPR000742; EG-like_dom.
 IPR013032; EGF-like_CS.
 IPR015497; EGF_rcpt_ligand. 

Pfam

  

SMART

 SM00181; EGF 

PROSITE

 PS00022; EGF_1
 PS50026; EGF_3 

PRINTS