Tag | Content |
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CPLM ID | CPLM-014684 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Serum response factor-binding protein 1 |
Protein Synonyms/Alias | SRF-dependent transcription regulation-associated protein; p49/STRAP |
Gene Name | Srfbp1 |
Gene Synonyms/Alias | |
Created Date | July 27, 2013 |
Organism | Rattus norvegicus (Rat) |
NCBI Taxa ID | 10116 |
Lysine Modification | Position | Peptide | Type | References |
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321 | PSSAKEQKPLPKVSS | acetylation | [1] | 436 | KIAVFQGKKITFDD* | acetylation | [1] |
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Reference | [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns. Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV. Cell Rep. 2012 Aug 30;2(2):419-31. [ PMID: 22902405] |
Functional Description | May be involved in regulating transcriptional activation of cardiac genes during the aging process. May play a role in biosynthesis and/or processing of SLC2A4 in adipose cells (By similarity). |
Sequence Annotation | MOD_RES 215 215 Phosphoserine (By similarity). MOD_RES 277 277 Phosphoserine (By similarity). MOD_RES 292 292 Phosphoserine (By similarity). MOD_RES 294 294 Phosphoserine (By similarity). |
Keyword | Coiled coil; Complete proteome; Cytoplasm; Phosphoprotein; Reference proteome; Transcription; Transcription regulation. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 442 AA |
Protein Sequence | MAADPSPPSA MAQPRPLNLN NEVVKMRKEV KRIRVLVIRK LVRSVSRLKS KKGSEDALLK 60 NQRRAQRLLQ EIHAMKELKP DVITKSALND DINFEKTCKK PDSTATERAI ARLAVHPLLK 120 RKVDALKAAI QAFKDARQNA PEAESSKSAS KESQCEDIPR SQAEASESQH PERTVVGEQK 180 GKDKDPTTAK KAGSGSKEKL AKGKQGPKAV ATPHSPGKPS EKGAGINSER QGAPTPGNHS 240 QGKASTRTTE DSVCEPDDNS ISKEEVSEEE KEYFDDSTEE RFYKQSSASE DSDSGDDFFI 300 GKVRRTRKKE CAVPSSAKEQ KPLPKVSSKT NTLETHWDIR NDKHKLIPEA RKLESVFFHS 360 LSGPKSSRRD PREQAPKNKA PDIPENEPPI QNKFTKSARR GFESAKQPSY APLHPSWEAS 420 RRRKEQQSKI AVFQGKKITF DD 442 |
Gene Ontology | GO:0005634; C:nucleus; IEA:Compara. GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell. GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW. GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. |
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