CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-014684
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Serum response factor-binding protein 1 
Protein Synonyms/Alias
 SRF-dependent transcription regulation-associated protein; p49/STRAP 
Gene Name
 Srfbp1 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Rattus norvegicus (Rat) 
NCBI Taxa ID
 10116 
Lysine Modification
Position
Peptide
Type
References
321PSSAKEQKPLPKVSSacetylation[1]
436KIAVFQGKKITFDD*acetylation[1]
Reference
 [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405
Functional Description
 May be involved in regulating transcriptional activation of cardiac genes during the aging process. May play a role in biosynthesis and/or processing of SLC2A4 in adipose cells (By similarity). 
Sequence Annotation
 MOD_RES 215 215 Phosphoserine (By similarity).
 MOD_RES 277 277 Phosphoserine (By similarity).
 MOD_RES 292 292 Phosphoserine (By similarity).
 MOD_RES 294 294 Phosphoserine (By similarity).  
Keyword
 Coiled coil; Complete proteome; Cytoplasm; Phosphoprotein; Reference proteome; Transcription; Transcription regulation. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 442 AA 
Protein Sequence
MAADPSPPSA MAQPRPLNLN NEVVKMRKEV KRIRVLVIRK LVRSVSRLKS KKGSEDALLK 60
NQRRAQRLLQ EIHAMKELKP DVITKSALND DINFEKTCKK PDSTATERAI ARLAVHPLLK 120
RKVDALKAAI QAFKDARQNA PEAESSKSAS KESQCEDIPR SQAEASESQH PERTVVGEQK 180
GKDKDPTTAK KAGSGSKEKL AKGKQGPKAV ATPHSPGKPS EKGAGINSER QGAPTPGNHS 240
QGKASTRTTE DSVCEPDDNS ISKEEVSEEE KEYFDDSTEE RFYKQSSASE DSDSGDDFFI 300
GKVRRTRKKE CAVPSSAKEQ KPLPKVSSKT NTLETHWDIR NDKHKLIPEA RKLESVFFHS 360
LSGPKSSRRD PREQAPKNKA PDIPENEPPI QNKFTKSARR GFESAKQPSY APLHPSWEAS 420
RRRKEQQSKI AVFQGKKITF DD 442 
Gene Ontology
 GO:0005634; C:nucleus; IEA:Compara.
 GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.
 GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.
 GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. 
Interpro
 IPR015158; Bud-site_select_BUD22. 
Pfam
 PF09073; BUD22 
SMART
  
PROSITE
  
PRINTS