CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-003201
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Galactitol-1-phosphate 5-dehydrogenase 
Protein Synonyms/Alias
  
Gene Name
 gatD 
Gene Synonyms/Alias
 b2091; JW2075 
Created Date
 July 27, 2013 
Organism
 Escherichia coli (strain K12) 
NCBI Taxa ID
 83333 
Lysine Modification
Position
Peptide
Type
References
23ESVIPEIKHQDEVRVacetylation[1]
105GFYSQCAKYDFIGSRacetylation[1]
124FAEYIVVKRKNVFALacetylation[1]
197AIDISSEKLALAKSFacetylation[1]
Reference
 [1] Acetyl-Phosphate Is a Critical Determinant of Lysine Acetylation in E. coli.
 Weinert BT, Iesmantavicius V, Wagner SA, Schölz C, Gummesson B, Beli P, Nyström T, Choudhary C.
 Mol Cell. 2013 Jul 25;51(2):265-72. [PMID: 23830618
Functional Description
 Converts galactitol 1-phosphate to tagatose 6-phosphate. 
Sequence Annotation
 METAL 38 38 Zinc 1; catalytic (By similarity).
 METAL 59 59 Zinc 1; catalytic (By similarity).
 METAL 89 89 Zinc 2 (By similarity).
 METAL 92 92 Zinc 2 (By similarity).
 METAL 95 95 Zinc 2 (By similarity).
 METAL 103 103 Zinc 2 (By similarity).
 METAL 144 144 Zinc 1; catalytic (By similarity).  
Keyword
 3D-structure; Complete proteome; Galactitol metabolism; Metal-binding; NAD; Oxidoreductase; Reference proteome; Zinc. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 346 AA 
Protein Sequence
MKSVVNDTDG IVRVAESVIP EIKHQDEVRV KIASSGLCGS DLPRIFKNGA HYYPITLGHE 60
FSGYIDAVGS GVDDLHPGDA VACVPLLPCF TCPECLKGFY SQCAKYDFIG SRRDGGFAEY 120
IVVKRKNVFA LPTDMPIEDG AFIEPITVGL HAFHLAQGCE NKNVIIIGAG TIGLLAIQCA 180
VALGAKSVTA IDISSEKLAL AKSFGAMQTF NSSEMSAPQM QSVLRELRFN QLILETAGVP 240
QTVELAVEIA GPHAQLALVG TLHQDLHLTS ATFGKILRKE LTVIGSWMNY SSPWPGQEWE 300
TASRLLTERK LSLEPLIAHR GSFESFAQAV RDIARNAMPG KVLLIP 346 
Gene Ontology
 GO:0008868; F:galactitol-1-phosphate 5-dehydrogenase activity; IEA:EC.
 GO:0016616; F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; IDA:EcoCyc.
 GO:0008270; F:zinc ion binding; IEA:InterPro.
 GO:0019404; P:galactitol catabolic process; IMP:EcoCyc. 
Interpro
 IPR013149; ADH_C.
 IPR013154; ADH_GroES-like.
 IPR002085; ADH_SF_Zn-type.
 IPR002328; ADH_Zn_CS.
 IPR011032; GroES-like.
 IPR016040; NAD(P)-bd_dom. 
Pfam
 PF08240; ADH_N
 PF00107; ADH_zinc_N 
SMART
  
PROSITE
 PS00059; ADH_ZINC 
PRINTS