UniProt Accession

 LYPL1_MOUSE; Q3UFF7; Q8R065 

Genbank Protein ID

 AK148533; BC027340 

Genbank Nucleotide ID

 BAE28604.1; AAH27340.1 

Protein Name

 Lysophospholipase-like protein 1 

Protein Synonyms/Alias

  

Gene Name

 Lyplal1 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Mus musculus (Mouse) 

NCBI Taxa ID

 10090 

Lysine Modification

Position	Peptide	Type	References
43	QGQREWIKHVLNQDL	acetylation	[1]
221	LNKTELEKLKSWILT	acetylation	[1]

Reference

 [1] Calorie restriction and SIRT3 trigger global reprogramming of the mitochondrial protein acetylome.
 Hebert AS, Dittenhafer-Reed KE, Yu W, Bailey DJ, Selen ES, Boersma MD, Carson JJ, Tonelli M, Balloon AJ, Higbee AJ, Westphall MS, Pagliarini DJ, Prolla TA, Assadi-Porter F, Roy S, Denu JM, Coon JJ.
 Mol Cell. 2013 Jan 10;49(1):186-99. [PMID: 23201123] 

Functional Description

 Does not exhibit phospholipase nor triacylglycerol lipase activity, able to hydrolyze only short chain substrates due to its shallow active site (By similarity). 

Sequence Annotation

 ACT_SITE 125 125 Charge relay system (By similarity).
 ACT_SITE 180 180 Charge relay system (By similarity).
 ACT_SITE 212 212 Charge relay system (By similarity).
 MOD_RES 2 2 N-acetylalanine (By similarity).  

Keyword

 Acetylation; Complete proteome; Cytoplasm; Hydrolase; Reference proteome. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 239 AA 

Protein Sequence

Gene Ontology

 GO:0005829; C:cytosol; IDA:MGI.
 GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
 GO:0042997; P:negative regulation of Golgi to plasma membrane protein transport; IMP:MGI.
 GO:0002084; P:protein depalmitoylation; IMP:MGI. 

Interpro

 IPR003140; PLipase/COase/thioEstase. 

Pfam

 PF02230; Abhydrolase_2 

SMART

  

PROSITE

  

PRINTS