| Tag | Content |
|---|
| CPLM ID | CPLM-023616 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Voltage-dependent anion-selective channel protein 3 |
Protein Synonyms/Alias | VDAC-3; hVDAC3; Outer mitochondrial membrane protein porin 3 |
Gene Name | VDAC3 |
Gene Synonyms/Alias | |
Created Date | July 27, 2013 |
Organism | Homo sapiens (Human) |
NCBI Taxa ID | 9606 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 20 | AAKDVFNKGYGFGMV | ubiquitination | [1] |
|
Reference | [1] Methods for quantification of in vivo changes in protein ubiquitination following proteasome and deubiquitinase inhibition. Udeshi ND, Mani DR, Eisenhaure T, Mertins P, Jaffe JD, Clauser KR, Hacohen N, Carr SA. Mol Cell Proteomics. 2012 May;11(5):148-59. [ PMID: 22505724] |
Functional Description | Forms a channel through the mitochondrial outer membrane that allows diffusion of small hydrophilic molecules (By similarity). |
Sequence Annotation | NP_BIND 242 244 NAD (By similarity).
NP_BIND 260 264 NAD (By similarity).
MOD_RES 2 2 N-acetylcysteine.
MOD_RES 20 20 N6-acetyllysine.
MOD_RES 48 48 Phosphotyrosine (By similarity).
MOD_RES 90 90 N6-acetyllysine.
MOD_RES 241 241 Phosphoserine (By similarity). |
Keyword | Acetylation; Alternative splicing; Complete proteome; Ion transport; Membrane; Mitochondrion; Mitochondrion outer membrane; NAD; Nucleotide-binding; Phosphoprotein; Porin; Reference proteome; Transmembrane; Transmembrane beta strand; Transport. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 283 AA |
Protein Sequence | MCNTPTYCDL GKAAKDVFNK GYGFGMVKID LKTKSCSGVM EFSTSGHAYT DTGKASGNLE 60
TKYKVCNYGL TFTQKWNTDN TLGTEISWEN KLAEGLKLTL DTIFVPNTGK KSGKLKASYK 120
RDCFSVGSNV DIDFSGPTIY GWAVLAFEGW LAGYQMSFDT AKSKLSQNNF ALGYKAADFQ 180
LHTHVNDGTE FGGSIYQKVN EKIETSINLA WTAGSNNTRF GIAAKYMLDC RTSLSAKVNN 240
ASLIGLGYTQ TLRPGVKLTL SALIDGKNFS AGGHKVGLGF ELEA 284 |
Gene Ontology | GO:0005741; C:mitochondrial outer membrane; TAS:ProtInc. GO:0046930; C:pore complex; IEA:UniProtKB-KW. GO:0000166; F:nucleotide binding; IEA:UniProtKB-KW. GO:0015288; F:porin activity; IEA:UniProtKB-KW. GO:0008308; F:voltage-gated anion channel activity; TAS:UniProtKB. GO:0015853; P:adenine transport; TAS:ProtInc. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |