CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-017387
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Putative homeodomain transcription factor 2 
Protein Synonyms/Alias
  
Gene Name
 PHTF2 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
60YDQQIWEKSVEQREIubiquitination[1]
Reference
 [1] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983] 
Functional Description
 May play a role in transcription regulation. 
Sequence Annotation
  
Keyword
 Alternative splicing; Complete proteome; DNA-binding; Nucleus; Reference proteome; Transcription; Transcription regulation. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 785 AA 
Protein Sequence
MASKVTDAIV WYQKKEFLSV ATTAPGPQQV LPGYCQCSLK DQGLFIQCLI GAYDQQIWEK 60
SVEQREIKFI KLGLRNKPKK TAHVKPDLID VDLVRGSAFA KAKPESPWTS LTRKGIVRVV 120
FFPFFFRWWL QVTSKVIFFW LLVLYLLQVA AIVLFCSTSS PHSIPLTEVI GPIWLMLLLG 180
TVHCQIVSTR TPKPPLSTGG KRRRKLRKAA HLEVHREGDG SSTTDNTQEG AVQNHGTSTS 240
HSVGTVFRDL WHAAFFLSGS KKAKNSIDKS TETDNGYVSL DGKKTVKSGE DGIQNHEPQC 300
ETIRPEETAW NTGTLRNGPS KDTQRTITNV SDEVSSEEGP ETGYSLRRHV DRTSEGVLRN 360
RKSHHYKKHY PNEDAPKSGT SCSSRCSSSR QDSESARPES ETEDVLWEDL LHCAECHSSC 420
TSETDVENHQ INPCVKKEYR DDPFHQSHLP WLHSSHPGLE KISAIVWEGN DCKKADMSVL 480
EISGMIMNRV NSHIPGIGYQ IFGNAVSLIL GLTPFVFRLS QATDLEQLTA HSASELYVIA 540
FGSNEDVIVL SMVIISFVVR VSLVWIFFFL LCVAERTYKQ RLLFAKLFGH LTSARRARKS 600
EVPHFRLKKV QNIKMWLSLR SYLKRRGPQR SVDVIVSSAF LLTISVVFIC CAQLLHVHEI 660
FLDCHYNWEL VIWCISLTLF LLRFVTLGSE TSKKYSNTSI LLTEQINLYL KMEKKPNKKE 720
ELTLVNNVLK LATKLLKELD SPFRLYGLTM NPLLYNITQV VILSAVSGVI SDLLGFNLKL 780
WKIKS 785 
Gene Ontology
 GO:0005783; C:endoplasmic reticulum; IDA:LIFEdb.
 GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
 GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
 GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.
 GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. 
Interpro
 IPR021980; TF_homeodomain_male. 
Pfam
 PF12129; Phtf-FEM1B_bdg 
SMART
  
PROSITE
  
PRINTS