CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-045248
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 U1 small nuclear ribonucleoprotein A 
Protein Synonyms/Alias
  
Gene Name
 SNRPA 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
20YINNLNEKIKKDELKubiquitination[1]
60GQAFVIFKEVSSATNubiquitination[1]
93TDSDIIAKMKGTFVEacetylation[2]
93TDSDIIAKMKGTFVEubiquitination[1]
95SDIIAKMKGTFVERDubiquitination[1, 3]
Reference
 [1] A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles.
 Wagner SA, Beli P, Weinert BT, Nielsen ML, Cox J, Mann M, Choudhary C.
 Mol Cell Proteomics. 2011 Oct;10(10):M111.013284. [PMID: 21890473]
 [2] Proteomic investigations of lysine acetylation identify diverse substrates of mitochondrial deacetylase sirt3.
 Sol EM, Wagner SA, Weinert BT, Kumar A, Kim HS, Deng CX, Choudhary C.
 PLoS One. 2012;7(12):e50545. [PMID: 23236377]
 [3] Integrated proteomic analysis of post-translational modifications by serial enrichment.
 Mertins P, Qiao JW, Patel J, Udeshi ND, Clauser KR, Mani DR, Burgess MW, Gillette MA, Jaffe JD, Carr SA.
 Nat Methods. 2013 Jul;10(7):634-7. [PMID: 23749302] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 129 AA 
Protein Sequence
MAVPETRPNH TIYINNLNEK IKKDELKKSL YAIFSQFGQI LDILVSRSLK MRGQAFVIFK 60
EVSSATNALR SMQGFPFYDK PMYAKTDSDI IAKMKGTFVE RDRKREKRKP KSQETPATKK 120
AVQGGGATP 129 
Gene Ontology
 GO:0000166; F:nucleotide binding; IEA:InterPro.
 GO:0017069; F:snRNA binding; IEA:InterPro.
 GO:0000398; P:mRNA splicing, via spliceosome; IEA:InterPro. 
Interpro
 IPR012677; Nucleotide-bd_a/b_plait.
 IPR000504; RRM_dom.
 IPR024888; U1_snRNP_A/U2_snRNP_B''. 
Pfam
 PF00076; RRM_1 
SMART
 SM00360; RRM 
PROSITE
 PS50102; RRM 
PRINTS