CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-030241
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Sacsin 
Protein Synonyms/Alias
  
Gene Name
 SACS 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
30GGRGISSKLDSLADEubiquitination[1, 2, 3, 4]
58SSRDDEAKGATSDFSubiquitination[3]
138TLILDSIKRLEMEKSubiquitination[3]
157LSVDVIYKLWPEASKubiquitination[2]
249SGTTPVRKVTPAWVRubiquitination[3]
338RFILDNLKPHLVAALubiquitination[3]
346PHLVAALKEAAQTRGubiquitination[3]
Reference
 [1] A data set of human endogenous protein ubiquitination sites.
 Shi Y, Chan DW, Jung SY, Malovannaya A, Wang Y, Qin J.
 Mol Cell Proteomics. 2011 May;10(5):M110.002089. [PMID: 20972266]
 [2] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983]
 [3] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961]
 [4] Integrated proteomic analysis of post-translational modifications by serial enrichment.
 Mertins P, Qiao JW, Patel J, Udeshi ND, Clauser KR, Mani DR, Burgess MW, Gillette MA, Jaffe JD, Carr SA.
 Nat Methods. 2013 Jul;10(7):634-7. [PMID: 23749302
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 374 AA 
Protein Sequence
IVLEEESTKD AQKTSWLVCN SVGGRGISSK LDSLADELKF VPIIGIAMPL SSRDDEAKGA 60
TSDFSGKAFC FLPLPPGEES STGLPVHISG FFGLTDNRRS IKWRELDQWR DPAALWNEFL 120
VMNVVPKAYA TLILDSIKRL EMEKSSDFPL SVDVIYKLWP EASKVKVHWQ PVLEPLFSEL 180
LQNAVIYSIS CDWVRLEQVY FSELDENLEY TKTVLNYLQS SGKQIAKVPG NVDAAVQLTA 240
ASGTTPVRKV TPAWVRQVLR KCAHLGCAEE KLHLLEFVLS DQAYSELLGL ELLPLQNGNF 300
VPFSSSVSDQ DVIYITSAEY PRSLFPSLEG RFILDNLKPH LVAALKEAAQ TRGFLFDEDS 360
NGKLKMVAVL ITSC 374 
Gene Ontology
  
Interpro
  
Pfam
  
SMART
  
PROSITE
  
PRINTS