UniProt Accession

 SEPT9_HUMAN; Q9UHD8; A8K2V3; B3KPM0; B4DTL9; B4E0N2; B4E274; B7Z654; Q96QF3; Q96QF4; Q96QF5; Q9HA04; Q9UG40; Q9Y5W4 

Genbank Protein ID

 AF123052; AJ312319; AJ312320; AJ312321; AJ312322; AF189712; AF189713; AF142408; AK022493; AK290368; AK056495; AK300270; AK303449; AK304143; AK299828; AK316473; BT007215; CH471099; CH471099; CH471099; BC021192; BC054004; AB023208; AL080131 

Genbank Nucleotide ID

 AAD39749.1; CAC42221.1; CAC42222.1; CAC42223.1; CAC42224.1; AAF23373.1; AAF23374.1; AAG27919.1; BAB14057.1; BAF83057.1; BAG51732.1; BAG62031.1; BAG64494.1; BAG65036.1; BAH13140.1; BAH14844.1; AAP35879.1; EAW89462.1; EAW89463.1; EAW89468.1; AAH21192.1; AAH54004.1; BAA76835.2; CAB45728.1 

Protein Name

 Septin-9 

Protein Synonyms/Alias

 MLL septin-like fusion protein MSF-A; MLL septin-like fusion protein; Ovarian/Breast septin; Ov/Br septin; Septin D1 

Gene Name

 SEPT9 

Gene Synonyms/Alias

 KIAA0991; MSF 

Created Date

 July 27, 2013 

Organism

 Homo sapiens (Human) 

NCBI Taxa ID

 9606 

Lysine Modification

Position	Peptide	Type	References
51	KFQDLGVKNSEPSAR	ubiquitination	[1]
168	PATDAAPKRVEIQMP	ubiquitination	[1]
253	APASRNEKAPVDFGY	ubiquitination	[1]
334	ITHDIEEKGVRMKLT	ubiquitination	[1]
427	NIVPVIAKADTLTLE	ubiquitination	[1]
458	GIDVYPQKEFDEDSE	ubiquitination	[1]
472	EDRLVNEKFREMIPF	ubiquitination	[1]

Reference

 [1] Landscape of the PARKIN-dependent ubiquitylome in response to mitochondrial depolarization.
 Sarraf SA, Raman M, Guarani-Pereira V, Sowa ME, Huttlin EL, Gygi SP, Harper JW.
 Nature. 2013 Apr 18;496(7445):372-6. [PMID: 23503661] 

Functional Description

 Filament-forming cytoskeletal GTPase (By similarity). May play a role in cytokinesis (Potential). May play a role in the internalization of 2 intracellular microbial pathogens, Listeria monocytogenes and Shigella flexneri. 

Sequence Annotation

 NP_BIND 305 312 GTP (By similarity).
 NP_BIND 445 453 GTP (By similarity).
 BINDING 339 339 GTP (By similarity).
 BINDING 365 365 GTP; via amide nitrogen (By similarity).
 BINDING 501 501 GTP; via amide nitrogen and carbonyl
 BINDING 516 516 GTP (By similarity).
 MOD_RES 30 30 Phosphoserine.
 MOD_RES 38 38 Phosphothreonine.
 MOD_RES 42 42 Phosphothreonine.
 MOD_RES 82 82 Phosphoserine.
 MOD_RES 85 85 Phosphoserine.
 MOD_RES 96 96 Phosphoserine.
 MOD_RES 142 142 Phosphothreonine.
 MOD_RES 160 160 Phosphoserine (By similarity).
 MOD_RES 278 278 Phosphotyrosine.
 MOD_RES 327 327 Phosphoserine.  

Keyword

 Alternative splicing; Cell cycle; Cell division; Chromosomal rearrangement; Complete proteome; Cytoplasm; Cytoskeleton; Disease mutation; GTP-binding; Nucleotide-binding; Phosphoprotein; Polymorphism; Reference proteome. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 586 AA 

Protein Sequence

Gene Ontology

 GO:0005874; C:microtubule; IDA:UniProtKB.
 GO:0048471; C:perinuclear region of cytoplasm; IDA:UniProtKB.
 GO:0001725; C:stress fiber; IDA:UniProtKB.
 GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
 GO:0003924; F:GTPase activity; TAS:ProtInc.
 GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
 GO:0051301; P:cell division; IEA:UniProtKB-KW.
 GO:0051291; P:protein heterooligomerization; IDA:UniProtKB. 

Interpro

 IPR000038; Cell_div_GTP-bd.
 IPR027417; P-loop_NTPase. 

Pfam

 PF00735; Septin 

SMART

  

PROSITE

  

PRINTS